Making sense of unfamiliar COVID-19 vaccines: How national origin affects vaccination willingness

Jensen, Eric; Wagoner, Brady; Pfleger, Axel; Herbig, Lisa; Watzlawik, Meike

doi:10.1371/journal.pone.0261273

Cited by 3 publications

(2 citation statements)

References 15 publications

(16 reference statements)

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“…Furthermore, the news coverage on the COVID-19 pandemic put the German public into the position to compare vaccines of different manufacturers and form a preference. Several studies show that many citizens prefer vaccines originating from their own country [ 48 – 50 ]. Individuals with a strong preference for a certain vaccine have a high vaccination intention when offered their preferred vaccine.…”

Section: Discussionmentioning

confidence: 99%

Infographics on risks associated with COVID-19 and the willingness to get the AstraZeneca vaccine: two randomized online experiments

Felgendreff,

Siegers,

Otten

et al. 2024

BMC Public Health

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Background Germans hesitated to get vaccinated with AstraZeneca in the COVID-19 pandemic after reports of blood clots. Methods In two preregistered online experiments with stratified randomization (Study 1 N = 824, Study 2: N = 1,056), we tested whether providing evidence-based benefit-risk information reduces the perceived risk of the AstraZeneca vaccine and the perceived probability of blood clots due to the AstraZeneca vaccine and increases the vaccination intention. In Study 1, participants saw no infographic (control) or one of two infographics (low vs. high exposure risk varied by the underlying incidence rates). Study 2 additionally varied the infographic design displaying the risk information (presented as table, circle icons, or manikin-like icons). Results The infographic decreased the risk perception of the vaccine compared to no infographic (Study 1: Cohens d = 0.31, 95% CI [0.14, 0.48]; Study 2: Cohens d = 0.34, 95% CI [0.06, 0.62]), but it did not influence the perceived probability of blood clots due to the AstraZeneca vaccine (Study 2: Cohens d = 0.05, 95% CI [-0.23, 0.33]). Also, the infographic design did not affect the perceived probability of blood clots (Study 2). The vaccination intention was not affected by viewing the infographic (Study 1: Cohens d = 0.04, 95% CI [-0.13, 0.21]; Study 2: Cohens d = 0.04, 95% CI [-0.24, 0.32]) nor the presented infection rate (Study 1: Cohens d = 0.07, 95% CI [-0.09, 0.24], Study 2: Cohens d = 0.01, 95% CI [-0.12, 0.15]) but by risk perceptions, sociodemographic characteristics, confidence in the AstraZeneca vaccine, and preference for alternative vaccines. Conclusions The evidence-based benefit-risk information helped putting the risk of vaccinations into perspective. Nevertheless, objective risk information alone did not affect vaccination intention that was low due to the preexisting lacking vaccine confidence.

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Section: Discussionmentioning

confidence: 99%

Infographics on risks associated with COVID-19 and the willingness to get the AstraZeneca vaccine: two randomized online experiments

Felgendreff,

Siegers,

Otten

et al. 2024

BMC Public Health

View full text Add to dashboard Cite

show abstract

“…A study in Germany identified demographic and political factors, with male left-wing voters who trust authorities, consume public media, and perceive COVID-19 as a significant health risk displaying the highest intention to vaccinate ( El-Far Cardo et al, 2021 ). Other studies of the Germany context establish links between vaccine hesitancy and conspiracy mindedness ( Jensen, Pfleger, et al, 2021 ) and between favorability of countries and foreign vaccines ( Jensen, Wagoner, et al, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

COVID-19 Vaccine Hesitancy in Denmark and Russia: A qualitative typology at the nexus of agency and health capital

Schneider‐Kamp

2022

SSM - Qualitative Research in Health

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Impact of vitamin D supplementation as COVID-19 vaccine adjuvant on sperm parameters and sex hormones in men with idiopathic infertility: Two separate pre–post studies

Zarepoor,

Nazari,

Pourmasumi

2024

Clin Exp Reprod Med

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Objective: Vitamin D deficiency is a major problem for human health worldwide. The mechanisms of vitamin D in the male reproductive system are unknown. After coronavirus disease 2019 (COVID-19) vaccines were developed, doubts were raised about their possible effects on male fertility. Based on vitamin D’s function in the immune system, its potential role as an adjuvant for COVID-19 vaccines is intriguing. The aims of this study were to assess the effects of vitamin D first on sperm parameters and sex hormones, and then as an immune adjuvant on sperm parameters and sex hormones after study participants had received their second doses of COVID-19 vaccines.Methods: Phase 1 (before the COVID-19 pandemic) included 72 men with idiopathic infertility, and phase 2 had 64 participants who received two doses of COVID-19 vaccines. Both groups were instructed to take 50,000 IU of vitamin D twice monthly for 3 months. Sperm parameters and sex hormones were assessed pre- and post-supplementation.Results: Regular vitamin D intake for 3 months significantly increased the participants’ vitamin D levels (p=0.0001). Both phases showed a positive correlation between vitamin D intake and sperm parameters. Vaccination had no negative effects on sperm parameters and sex hormones. Vitamin D was associated with follicle-stimulating hormone (p=0.02) and testosterone (p=0.0001) in phase 2 after treatment. Conclusion: Our results support vitamin D supplementation as an immune adjunct to COVID-19 vaccination for improving sperm parameters and hormone levels. COVID-19 vaccination is not harmful for male fertility potential, and vitamin D is an effective factor for male fertility.

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Making sense of unfamiliar COVID-19 vaccines: How national origin affects vaccination willingness

Cited by 3 publications

References 15 publications

Infographics on risks associated with COVID-19 and the willingness to get the AstraZeneca vaccine: two randomized online experiments

Infographics on risks associated with COVID-19 and the willingness to get the AstraZeneca vaccine: two randomized online experiments

COVID-19 Vaccine Hesitancy in Denmark and Russia: A qualitative typology at the nexus of agency and health capital

Impact of vitamin D supplementation as COVID-19 vaccine adjuvant on sperm parameters and sex hormones in men with idiopathic infertility: Two separate pre–post studies

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