Major Morbidity and Mortality Rates in Craniofacial Surgery: An Analysis of 8101 Major Procedures

Czerwiński, Marcin; Hopper, Richard A.; Gruss, Joseph S.; Fearon, Jeffrey A.

doi:10.1097/prs.0b013e3181da87df

Cited by 134 publications

(99 citation statements)

References 24 publications

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“…3 Blood loss is the main cause of mortality after major craniofacial procedures in children. 4 Reported transfusion volumes for pediatric patients undergoing surgical correction of synostotic calvarial sutures vary between 20% and 500% of estimated blood volume. 3 Erythrocyte transfusion is associated with many serious adverse events, including increased mortality in the pediatric surgical population.…”

mentioning

confidence: 99%

Intraoperative Tranexamic Acid Reduces Blood Transfusion in Children Undergoing Craniosynostosis Surgery

Dadure¹,

Sauter²,

Bringuier³

et al. 2011

Anesthesiology

209

183

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mentioning

confidence: 99%

Intraoperative Tranexamic Acid Reduces Blood Transfusion in Children Undergoing Craniosynostosis Surgery

Dadure¹,

Sauter²,

Bringuier³

et al. 2011

Anesthesiology

209

183

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“…La dependencia y la independencia compartida por el cerebro y la cara en diferentes puntos de tiempo pueden explicar por qué el cerebro y las malformaciones faciales se ven a menudo juntos, pero también pueden explicar como un desarrollo facial anormal puede ocurrir en presencia de un cerebro aparentemente normal. [17][18][19][20] Diversos estudios demuestran que la ausencia de proteínas Sonic Hedgehog SHH, origina malformaciones como la holoprosencefalia, hipotelorismo, ciclopia, hipoplasia medio facial, así como labio y paladar hendido. Los genes Hox, anomalías en la expresión resultan en la malformación de cualquiera de las estructuras derivada de los arcos.…”

Section: Resultado Y Discusiónunclassified

Craneosinostosis: Revisión de literatura

2016

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ResumenLas craneosinostosis consisten en el cierre prematuro parcial o total de una o más suturas craneales, con una incidencia de 1 de cada 1000 a 3000 nacidos vivos, con mayor prevalencia en varones. Dentro del contexto de las craneosinostosis primaria, la escafocefalia o craneosinostosis sagital es la forma más frecuente y conocida. Al presentarse en un período de vida donde el crecimiento cráneo cerebral es muy importante, ocasiona en los niños una deformidad craneal característica que debe ser corregida, ya que en caso contrario y al ser progresiva, la afectación estética puede ser muy indeseable; las alteraciones funcionales que se pueden presentar van desde aumento de la presión intracraneana, hasta convulsiones, entre otras. Se realizó una búsqueda en bases de datos como PUDMED, RIMA, MEDLINE, MEDSCAPE de revisiones de temas, guías de manejo, artículos y análisis estadísticos, en idioma inglés, donde se encontraron 1.469 referencias. Después de una primera mirada de los artículos a través de sus resúmenes comprendidos en el periodo de tiempo año 2000 a 2014, finalmente se seleccionaron 50 artículos en texto completo abarcando el tema en su totalidad que cumplían los requisitos de búsqueda.Palabras clave: Craneosinostosis; sinostosis; suturas craneales. (Fuente: DeCS, Bireme). AbstractThe craniosynostosis consist of full or partial premature closure of one or more cranial sutures, with an incidence of 1 in 1000 3000 live births, with higher prevalence in males. Within the context of primary craniosynostosis, sagittal craniosynostosis scaphocephaly or is the most common and known form. To occur over a period of life where growth cranium is very important causes in children a characteristic skull deformity should be corrected, since otherwise and being progressive, aesthetic involvement can be very undesirable; functional alterations that may occur include increased intracranial pressure, seizures and others. A search was conducted in databases such as PUBMED, RIMA, MEDLINE, Medscape reviews issues, management guides, articles and statistical analysis, in english, where they found 1,469 references. After a first look at the articles through their summaries included in the period 2000 to 2014, finally 50 articles were selected in full text covering the subject fully meeting the conditions search.

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“…The mortality has been reported to be around 0.1-2.2% (41). This depends on patient selection and patient series.…”

Section: Review Of Diagnostical Methods and Discussionmentioning

confidence: 99%

Diagnosis and treatment of craniosynostosis: Vilnius team experience

Zaleckas¹,

Neverauskienė²,

Daugelavičius³

et al. 2015

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Background. The aim of the study was to review the methods of diagnosis of craniosynostosis and to analyze Vilnius (Lithuania) team experience of surgical treatment, surgical methods, aspects of anesthesia for patients with craniosynostosis and to present early results of surgical treatment.Materials and methods. A retrospective review of all patients with various types of craniosynostosis treated surgically during the period from 1 January 2009 to 31 December 2014 was performed. The following data were analyzed: age, type of deformity, surgical technique, surgical time, methods and course of anesthesia, intra-and postoperative complications, parents' satisfaction, head form.Results. 24 patients were treated. The mean patient's age at the time of surgery was 13.47 ± 8.2 months (min 7.3, max 46.5). Eliminating 3 patients whose age at the time of surgery was over 2 years (24.5, 29 and 46 months, respectively), the mean age of other 21 patients was 10.63 ± 1.77 (min 7.3, max 14.1) months. There were 9 cases of isolated trigonocephaly (37.5%), 7 cases of isolated scaphocephaly (29.2%), 7 cases of isolated anterior plagiocephaly (29.2%) and 1 case of posterior plagiocephaly combined with scaphocephaly (4.17%). All craniosynostoses were diagnosed clinically and diagnosis was confirmed with computed tomographic scanning. The median duration of surgery was 336.47 ± 59.63 minutes (min 308.13, max 364.82). The medium stay in the intensive care unit was 2.53 ± 1.28 days (min. 1.92, max 3.14). In all cases rigid osteosynthesis was performed. 2 children were diagnosed with syndromic craniofacial abnormalities. In 23 (95.83%) cases an intraoperative or postoperative blood transfusion was required. In 24 treated patients there was no mortality. During the early and late postoperative period no infections, CSF leakage and dural tears were observed. No neurological impairments or any signs of neurological deficits were observed by any of the treated patients. In all of cases parents were satisfied with their children's changed head shape and aesthetic results.Conclusions. Cranioplasties for correction of craniosynostosis give good aesthetic results and this is a safe method, which helps to correct the head shape as well as improves the social adaptation of patients.

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Major Morbidity and Mortality Rates in Craniofacial Surgery: An Analysis of 8101 Major Procedures

Cited by 134 publications

References 24 publications

Intraoperative Tranexamic Acid Reduces Blood Transfusion in Children Undergoing Craniosynostosis Surgery

Intraoperative Tranexamic Acid Reduces Blood Transfusion in Children Undergoing Craniosynostosis Surgery

Craneosinostosis: Revisión de literatura

Diagnosis and treatment of craniosynostosis: Vilnius team experience

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