Major cardiac event risk scores estimated with gated myocardial perfusion imaging in Japanese patients with coronary artery disease

Abstract

The risk scores obtained from this study are useful to predict MCEs in Japanese patients with CAD and are expected to be useful for management and informed consent of high-risk CAD patients.

Prognostic Value of Major Cardiac Event Risk Score Estimated With Gated Myocardial Perfusion Imaging in Japanese Patients With Coronary Artery Disease

“…5,21) LVEF is one of the predictors useful in the estimation of MCE risks with the Heart Risk Table. However, in a previous study, 10) we found that LVEF was an independent significant predictor of cardiac death but not of MCEs. Therefore, we have separately prepared two different equations to predict the risks of MCEs and cardiac death.…”

“…All study participants provided written informed consent prior to inclusion in the study. Tctetrofosmin myocardial perfusion SPECT 8,[10][11][12][13][14][15][16] at Nihon University Itabashi Hospital between October 2004 and March 2013 and who had a significant stenosis with 75% or greater narrowing of the arterial diameter detected by coronary angiography (CAG) performed after confirmation of at least 5% ischemia by the SPECT. The patients underwent treatment including revascularization and medication, and thereafter, were re-evaluated with the SPECT during a chronic phase and followed up to confirm prognosis for at least one year.…”

“…10) In the present study, we attempted to verify the prognostic values of the CERS before and after treatment in Japanese patients with CAD.…”

“…When a patient had multiple MCEs, only the first event was taken as the study endpoint. Estimated MCE risks within 3 years with the CERS: MCE risk (%) within 3 years before and after treatment was estimated with the following formula 10) predicting the risk of MCEs except severe heart failure on the basis of 4 predictors consisting of age, diabetes mellitus (DM), SSS, and eGFR:…”

Cardiac Event Risk Stratification Using Nuclear Cardiology in Japanese Patients with Coronary Artery Disease

“…Therefore we performed a three-year prognostic follow-up study in 2,579 patients who underwent myocardial perfusion SPECT in our hospital to prepare a regression equation suitable to predict the risk of MCEs excepting heart failure and reported our original cardiac event risk score (CERS) [39]. The following is a description of the creation of the CERS according to our report.…”