Major adverse cardiac events after first time elective isolated coronary artery bypass grafting: A retrospective cohort study

Kamel, Ahmed Tarek Hussein; Hassouna, Ahmed; El-Hamid, Hossam El-Din Ashour Abd; Hikal, Tamer

doi:10.1016/j.jescts.2018.11.001

Cited by 2 publications

(2 citation statements)

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“…The early mortality of CABG is reported to be between 1-7.4% in the literature (1 -4). Although there is plenty of data from both our country and abroad in the literature on mortality, there is no definite consensus on MAE definition (4,5). Moreover, we believe there is insufficient data on MAE development after CABG, especially in our country.…”

Section: Introductionmentioning

confidence: 84%

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Factors Affecting Major Adverse Effects After Coronary Artery Bypass Surgery

Limandal,

Özkara

2024

Kocatepe Tıp Dergisi

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OBJECTIVE: The present study aimed to evaluate the patient population who underwent coronary artery bypass grafting (CABG) operation in terms of mortality and major adverse effects (MAE) incidence and examine the factors affecting MAE incidence. MATERIAL AND METHODS: 169 consecutive patients who underwent CABG surgery between January 2017 and December 2019 were retrospectively analyzed. Mortality, myocardial infarction, reoperation, cardiac tamponade, stroke, renal failure, sternal infection, need for extracorporeal membrane oxygenator and cardio pulmonary resuscitation were defined as MAO. RESULTS: The mean age of the patients was 63.19 ±0.72 years, the mean duration of cardiopulmonary bypass (CPB) was 106.95 ±27 minutes, and the mean duration of aortic cross-clamp was 44.87 ±1.05 minutes. Extracorporeal membrane oxygenator support was provided to 11 (6.5%) patients, 7 (4.1%) patients underwent reoperation, 5 (3%) patients experienced a postoperative stroke, 5 (3%) patients required cardiopulmonary resuscitation, and postoperative myocardial infarction was observed in 1 (0.6%) patient. In total, MAE was determined in 28 (16.6%) patients. Mortality occurred in 9 (5.3%) patients. In the univariate analysis, Euroscore, mean arterial pressure during CPB, and ultrafiltration volume were associated with MAE (p=0.004, p=0.026, and p=0.037, respectively). However, in multivariate analysis, only Euroscore (odds ratio: 1.453, 95% CI 1.166-1.811 p=0.001) and ultrafiltration volume (odds ratio:-0.002, 95% CI 0.996-1 p=0.04) were correlated to MAE. CONCLUSIONS: In our study, we observed that high Euroscore levels increased not only mortality but also the incidence of MAO, and increased ultrafiltration volumes reduced the incidence of MAO. We believe that it should be kept in mind during CABG surgery that appropriate ultrafiltration and CPB strategy can reduce the incidence of MAO.

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Section: Introductionmentioning

confidence: 84%

“…Mortality after CABG operations is reported to be between 1-7.4% (4,35,36). A study by Kamel et al revealed that the incidence of mortality as a MAE was 18.7% (4).…”

Section: Discussionmentioning

confidence: 99%