Maintenance of the virus-specific CD8+ T-cell repertoire: Implications for vaccine strategies

Abstract

General introduction and scope of this thesisMethodologies for TCR repertoire analysis PART 1: MAINTENANCE OF THE T-CELL REPERTOIRE Review: How age and infection history shape the antigen-specific CD8 + T-cell repertoire: Implications for vaccination strategies in older adults Aging Cell, 2020 Age and CMV-infection jointly affect the EBV-specific CD8 + T-cell repertoire Frontiers in Aging, 2021 Latent CMV-infection is associated with lower influenza virus-specific memory T-cell frequencies, but not with an impaired T-cell response to acute influenza virus infection Frontiers in Immunology, 2021 Longitudinal characterization of the mumps-specific HLA-A2 restricted T-cell response after mumps virus infection Vaccines, 2021