1969
DOI: 10.1530/jrf.0.0180129
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Maintenance of Luteal Function During Unilateral Pregnancy in the Rat

Abstract: The prolongation of pseudopregnancy in the rat as a result of hysterectomy (melampy, Anderson & Kragt, 1964) or massive deciduoma (Velardo, Olsen, Hisaw & Dawson, 1953; Melampy et al., 1964) suggests that a luteolyticprinciple is produced by the uterine endometrium. There is evidence that the proposed luteolysin acts locally: pseudopregnancy is extended in rats following excision

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Cited by 3 publications
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“…The experiment indicates also that the placental influence on ovarian activity is entirely or predominantly systemic. This systemic luteotrophic action of the placentae might override any luteo¬ lytic effect of the mouse uterus, as has been suggested for the rat (Strauss & Lindner, 1969) and the guinea-pig (Deanesly, 1967). However, the experiments described above which demonstrate that the uterus has no effect on the life of the CL after placental removal make such an explanation unnecessary in mice.…”
Section: Discussionmentioning
confidence: 88%
“…The experiment indicates also that the placental influence on ovarian activity is entirely or predominantly systemic. This systemic luteotrophic action of the placentae might override any luteo¬ lytic effect of the mouse uterus, as has been suggested for the rat (Strauss & Lindner, 1969) and the guinea-pig (Deanesly, 1967). However, the experiments described above which demonstrate that the uterus has no effect on the life of the CL after placental removal make such an explanation unnecessary in mice.…”
Section: Discussionmentioning
confidence: 88%