Maintenance Cognitive-Behavioral Therapy and Manualized Psychoeducation in the Treatment of Recurrent Depression: A Multicenter Prospective Randomized Controlled Trial

Abstract

The results indicate that maintenance CBT has significant effects on the prevention of relapse or recurrence only in patients with a high risk of depression recurrence. For patients with a moderate risk of recurrence, nonspecific effects and structured patient education may be equally effective.

The effectiveness and cost-effectiveness of mindfulness-based cognitive therapy compared with maintenance antidepressant treatment in the prevention of depressive relapse/recurrence: results of a randomised controlled trial (the PREVENT study)

“…This study provides important evidence that MBCT-TS may confer ongoing protection for patients who would like an alternative to m-ADM. The results further suggest that psychosocial treatments, such as MBCT and CBT, 117,121,124 offer added value for patients who need them most, that is, those at highest risk of depressive relapse/recurrence. However, studies have tended to operationalise risk in somewhat different ways (e.g.…”

“…Many patients with recurrent depression may have been on m-ADM for many years and for a variety of reasons would prefer to learn skills that they can use to stay well. The results further suggest that psychosocial treatments such as MBCT and CBT 117,121,124 offer added value for patients who need them most, that is, those at highest risk of depressive relapse/recurrence. The investment of effort by these patients in learning the skills taught in psychosocial treatments such as CBT and MBCT pays off.…”

“…For example, in a two-arm RCT with 21 months' follow-up, relapse/recurrence rates were 51% for maintenance CBT and 60% for psychoeducation but, among those at greatest risk, CBT conferred greater protection than psychoeducation. 121 A reported history of abuse and adversity is associated with worse outcomes among people who suffer depression. 122 Perhaps MBCT confers resilience in this group at highest risk because patients learn skills that address some of the underlying mechanisms of relapse/recurrence, a question that we will seek to explore in a subsequent publication from this trial.…”

CBT in Affective Disorders – New Frontiers

“…In a more recent, prospective, randomized, observer blinded multicenter study Stangier and colleagues compared the rates of relapse in 180 completely remitted depressed patients with three or more previous episodes who either received TAU plus Maintenance Cognitive Therapy (MCT) or TAU plus Manualized Psychoeducation (MAPE) for eight months [53]. Afterwards the patients were followed up for one year.…”

Survey of the Effect of Group Pcycoeducation on Self-Efficacy in Patients with Intestinal Stoma

“…), don't have enough personal effectiveness, can be trained to trust their ability to succeed more, strengthen their selfworth, and the possibility of being successful (9). Several studies have shown that educational programs for pa- tients based on self-training can be an effective strategy to improve knowledge, skills, self-efficacy, and repairing behaviors associated with the disease to help contribute in their treatment (10,11). Sadeghi SenaAbadi also pointed in his study that self-care education is effective on patients with stoma (12).…”