2007
DOI: 10.1080/00365510601110130
|View full text |Cite
|
Sign up to set email alerts
|

Maintained malnutrition produces a progressive decrease in (OPG)/RANKL ratio and leptin levels in patients with anorexia nervosa

Abstract: The decrease in the OPG/RANKL ratio in girls with AN could partly explain the increase in bone loss that occurs in these patients.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

2
20
0

Year Published

2009
2009
2018
2018

Publication Types

Select...
4
3

Relationship

0
7

Authors

Journals

citations
Cited by 24 publications
(22 citation statements)
references
References 20 publications
2
20
0
Order By: Relevance
“…Our earlier investigations revealed that serum sRANKL was increased while the OPG/sRANKL ratio was significantly decreased [21,22,61]. Similar results were obtained by Munoz-Calvo et al [57]. However, no complex research studies have been carried out so far in girls with AN concerning the relationships between LP, ADIPO, RES, VISF, APE-36, APE-12 and bone metabolism, OPG and its soluble ligand sRANKL.…”
Section: Prace Oryginalnesupporting
confidence: 83%
See 3 more Smart Citations
“…Our earlier investigations revealed that serum sRANKL was increased while the OPG/sRANKL ratio was significantly decreased [21,22,61]. Similar results were obtained by Munoz-Calvo et al [57]. However, no complex research studies have been carried out so far in girls with AN concerning the relationships between LP, ADIPO, RES, VISF, APE-36, APE-12 and bone metabolism, OPG and its soluble ligand sRANKL.…”
Section: Prace Oryginalnesupporting
confidence: 83%
“…Munoz-Calvo et al [57] also reported a significant decrease in the OPG/RANKL ratio correlated with an increase in serum RANKL as well as a positive and significant correlation between the OPG/RANKL ratio and BMD. However, they did not observe a significant OPG increase in serum of girls with AN, or any relationships between OPG, RANKL and BMD.…”
Section: Prace Oryginalnementioning
confidence: 88%
See 2 more Smart Citations
“…On the other hand, serum sRANKL [25][26][27][28][29][30][31] and/or OPG levels [23][24][25][26][27][28][29][30][31] are significantly increased in girls with AN while the OPG/sRANKL ratio is significantly decreased [32,[25][26][27][28][29][30][31]. MunozCalvo et al [32] were the only researchers who did not find significant changes in OPG levels in girls with AN who exhibited a significantly increased sRANKL level and OPG/sRANKL suppression. Our previous studies [26][27][28][29][30][31] indicate some desynchronisation between the RANKL/RANK/OPG system and bone remodelling (especially bone resorption) in girls with AN.…”
mentioning
confidence: 96%