Necrotizing gingivitis, necrotizing periodontitis and necrotizing stomatitis are classified together under the common name necrotizing periodontal disease (NPD). The etiology is associated with bacterial infection (fusobacteria and spirochetes), but NPD is also predisposed by various factors: local (poor oral hygiene, preexisting plaque-induced gingivitis, local trauma, smoking, alcohol abuse) and systemic factors (emotional stress, fatigue and insomnia, social economic status and altered host response, malnutrition or systemic diseases).