Magnitude of erectile dysfunction and associated factors among adult diabetic men on follow-up at Goba and Robe hospitals, Bale Zone, South East Ethiopia: hospital-based cross-sectional study

Mesfin, Telila; Tekalegn, Yohannes; Adem, Ahmednur; Seyoum, Kenbon; Geta, Girma; Sahiledengle, Biniyam; Mesfin, Eshetu; Zenbaba, Demisu; Desta, Fikreab; Beressa, Girma; Tsegaye, Mesfin; Ejigu, Neway; Gomora, Degefa

doi:10.1186/s12902-023-01489-x

Cited by 3 publications

(1 citation statement)

References 58 publications

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“…In certain African cultures, male sexual competence is considered a symbol of honor and dignity. Consequently, men may experience anxiety and stress regarding their sexual ability, which can further affect their sexual function ( 79 ).…”

Section: Discussionmentioning

confidence: 99%

Risk factors for erectile dysfunction in diabetes mellitus: a systematic review and meta-analysis

Dilixiati,

Waili,

Tuerxunmaimaiti

et al. 2024

Front. Endocrinol.

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BackgroundPrevious studies have established that diabetes mellitus (DM) markedly raises the risk of developing erectile dysfunction (ED). Despite extensive investigations, the risk factors associated with ED in diabetic men have yet to be unequivocally determined, owing to incongruent and inconclusive results reported in various studies.ObjectiveThe objective of this systematic review and meta-analysis was to assess the risk factors for ED in men with DM.MethodsA comprehensive systematic review was conducted, encompassing studies published in the PubMed, Scopus and Embase databases up to August 24th, 2023. All studies examining the risk factors of ED in patients with DM were included in the analysis. To identify significant variations among the risk factors, odds ratios (ORs) and their corresponding 95% confidence intervals (CIs) were employed. The risk of bias was evaluated using the Newcastle-Ottawa Scale(NOS) for longitudinal studies and the Agency for Healthcare Research and Quality Scale(AHRQ) for cross-sectional studies.ResultsA total of 58 studies, including a substantial participant pool of 66,925 individuals diagnosed with DM, both with or without ED, were included in the meta-analysis. Mean age (OR: 1.31, 95% CI=1.24-1.37), smoking status (OR: 1.32, 95% CI=1.18-1.47), HbA1C (OR: 1.44, 95% CI=1.28-1.62), duration of DM (OR: 1.39, 95% CI=1.29-1.50), diabetic neuropathy (OR: 3.47, 95% CI=2.16-5.56), diabetic retinopathy (OR: 3.01, 95% CI=2.02-4.48), diabetic foot (OR: 3.96, 95% CI=2.87-5.47), cardiovascular disease (OR: 1.92, 95% CI=1.71-2.16), hypertension (OR: 1.74, 95% CI=1.52-2.00), microvascular disease (OR: 2.14, 95% CI=1.61-2.85), vascular disease (OR: 2.75, 95% CI=2.35-3.21), nephropathy (OR: 2.67, 95% CI=2.06-3.46), depression (OR: 1.82, 95% CI=1.04-3.20), metabolic syndrome (OR: 2.22, 95% CI=1.98-2.49), and diuretic treatment (OR: 2.42, 95% CI=1.38-4.22) were associated with increased risk factors of ED in men with DM.ConclusionOur study indicates that in men with DM, several risk factors for ED have been identified, including mean age, HbA1C, duration of DM, diabetic neuropathy, diabetic retinopathy, diabetic foot, cardiovascular disease, hypertension, microvascular disease, vascular disease, nephropathy, depression, metabolic syndrome, and diuretic treatment. By clarifying the connection between these risk factors and ED, clinicians and scientific experts can intervene and address these risk factors, ultimately reducing the occurrence of ED and improving patient management.

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Section: Discussionmentioning

confidence: 99%

Risk factors for erectile dysfunction in diabetes mellitus: a systematic review and meta-analysis

Dilixiati,

Waili,

Tuerxunmaimaiti

et al. 2024

Front. Endocrinol.

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Erectile Dysfunction in Men with and without Type 2 Diabetes Mellitus at Livingstone University Teaching Hospital, Zambia: A cross-sectional study

Muchaili,

Mweene,

Hamooya

et al. 2024

Preprint

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BackgroundErectile dysfunction (ED) is frequently undiagnosed in males with type 2 diabetes mellitus (T2DM), despite its high prevalence. Early detection of ED in T2DM is crucial for effective treatment and prevention of severe complications such as cardiovascular events. This study explores the prevalence of ED and its associated factors in males with and without T2DM at Livingstone University Teaching Hospital (LUTH), Zambia.MethodologyWe conducted a cross-sectional study at LUTH among 42 males aged ≥18 years (22 with and 20 without T2DM). T2DM diagnosis was confirmed through medical records, and erectile dysfunction was assessed using the International Index of Erectile Function (IIEF-5) questionnaire. Logistic regression identified factors associated with ED, with significance set at a p-value less than 0.05ResultsThe overall prevalence of ED was 74% (31/42). Among T2DM participants, the prevalence of ED was 91% (20/22; 95% confidence interval (CI) 70.8-98.9) whereas among the non-diabetic participants, the prevalence was 55% (11/20; 95%CI 31.5-76.9). The majority [40% (8/20)] of the T2DM participants with ED had mild ED, 35% (7/20) had mild to moderate ED, 15% (3/20) had moderate ED and 10% (2/20) had severe ED. 54.5% (6/11)] of the non-T2DM participants with ED had mild ED, 36.4% (4/11) had mild to moderate ED, 9.1% (1/11) had moderate ED, and none had severe ED. In the multivariable analysis, employed individuals had lower odds of erectile dysfunction compared to the unemployed (OR 0.01, 95% CI 0.00 - 0.84, p = 0.041); while elevated plasma creatinine levels were associated with an increased risk of erectile dysfunction (OR 1.22, 95% CI 1.03 - 1.45, p = 0.021).ConclusionThis study underscores a significant prevalence of ED, particularly heightened in T2DM participants; and significantly associated with plasma creatinine levels and employment status. The findings highlight the need for comprehensive assessment and management of ED in T2DM individuals. There is a need for further research with larger sample sizes to validate the findings and for a clearer understanding of associated factors and identification of effective targeted interventions.

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Andropause: A Neglected Disease Entity

Folorunsho Ajayi,

David,

Ayodele

et al. 2024

OBM Geriatr

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This review aims to bring attention to the growing issue of andropause, a condition that affects men as they age. The literature was identified by searching the major bibliographic databases, including PubMed, Google Scholar, EBSCOhost, Web of Science, and CINAHL. Studies were included if they focused on strategies for reducing and preventing andropause, published between 1980 and 2023. Andropause, which is often overlooked and misconceived, is the result of a decrease in testosterone production and can result in physical and psychological symptoms such as fatigue, weight gain, decreased libido, and depression. This paper reviews the literature on the prevalence, detection, and management of andropause. It is important for the medical community to recognize andropause, as diagnosing and treating the condition can significantly improve the quality of life. The review canvases several studies to understand andropause comprehensively, highlighting various biomarkers and diagnostic criteria, possible therapies, and potential risks and complications associated with the condition. In addition, this review offers practical suggestions to health professionals, helping them recognize patients at risk of andropause, assess patients for the condition, and provide appropriate treatments. Furthermore, it emphasizes the importance of regular screening and active monitoring for any possible early warning signs of andropause. This review provides a comprehensive overview of andropause, from identification to management. It demonstrates the need for increased awareness and acknowledgment of andropause among medical professionals in order to ensure that all men get the support they need throughout the aging process.

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Magnitude of erectile dysfunction and associated factors among adult diabetic men on follow-up at Goba and Robe hospitals, Bale Zone, South East Ethiopia: hospital-based cross-sectional study

Cited by 3 publications

References 58 publications

Risk factors for erectile dysfunction in diabetes mellitus: a systematic review and meta-analysis

Risk factors for erectile dysfunction in diabetes mellitus: a systematic review and meta-analysis

Erectile Dysfunction in Men with and without Type 2 Diabetes Mellitus at Livingstone University Teaching Hospital, Zambia: A cross-sectional study

Andropause: A Neglected Disease Entity

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