Magnitude and Associated Factors of Non-Adherence to Highly Active Antiretroviral Therapy among Children in Fiche Hospital, North Shewa, Ethiopia, 2016

Feyissa, Adunya

doi:10.4172/2376-0419.1000170

Cited by 4 publications

(6 citation statements)

References 8 publications

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“…14 However, it was less than different researches done in Ethiopia which were 90% to 94%, 10-12 91% in Nigeria, 8 and 89.1% in South Africa. 7 However, the current study was higher than studies conducted in Fiche, Ethiopia which was 64.2%, 9 66.7% in Ambo (Ethiopia), 15 79.8% in South Sudan, 4 42.7% in Uganda, 16 and 47.5% in Ghana. 6 The discrepancies might be due to differences in the measurement of adherence assessment used and differences in clinical settings.…”

Section: Discussioncontrasting

confidence: 78%

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Adherence to Antiretroviral Therapy and Associated Factors Among Children Living With HIV in East Wallaga Zone Public Health Institutions, Ethiopia

Alemayehu,

Etana,

Abebe

2023

J Int Assoc Provid AIDS Care

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Background: Adherence to antiretroviral therapy (ART) in children is influenced by multiple factors that can be linked to carer and children. The study aimed to assess the level of adherence to ART and its associated factors among children attending ART in East Wallaga zone public health institutions, Ethiopia. Methods: An institution-based cross-sectional study was conducted among ART attending children in East Wallaga public health facilities. Pretested and structured questionnaires were used to collect data. To determine the level of significance, bivariate and multiple logistic regressions and 95% confidence intervals were performed. Results: One hundred eighty-five (78.1%) of the 237 study participants’ caregiver stated that their children had adhered to ART in the month preceding the interview. The male children, children from urban, disclosure the human immunodeficiency virus status to the children, proximity to health facilities, good relationship of caregivers with healthcare providers, and children on first-line regimens were strongly linked with ART adherence. Conclusion: The adherence rate obtained in this study was less than 95%, which is an optimal level of adherence recommended by the World Health Organization. Therefore, much work has to be done to optimize adherence to ART.

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Section: Discussioncontrasting

confidence: 78%

“…Moreover, a previous study conducted in Ethiopia showed that 79.1% in 64.2% to 94% children were adherent to ART which was lower than adherent recommended by World Health Organization (WHO). 9-12…”

Section: Introductionmentioning

confidence: 99%

Adherence to Antiretroviral Therapy and Associated Factors Among Children Living With HIV in East Wallaga Zone Public Health Institutions, Ethiopia

Alemayehu,

Etana,

Abebe

2023

J Int Assoc Provid AIDS Care

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“…This difference might be due to study design (cross sectional vs cohort). It was also higher than study in Uganda (overall adherence status of 79.1%) (26), South Wallo zone which provided an adherence status of 78.6% (18), in Fiche Hospital that showed adherence rate of 74% (27). This difference could be due to the fact small sample size (120) in Fiche Hospital as compared to ours (282).…”

Section: Discussioncontrasting

confidence: 73%

Children’s Adherence to Antiretroviral Therapy and Associated Factors: Multi-center Cross-sectional Study

Gemechu

Habtamu

Zarihun

2022

Preprint

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Background- Sub- optimal adherence to antiretroviral therapy will lead drug resistance, treatment failure, clinical deterioration, death and failure to thrive in children. Studies conducted among children below 15 years old were limited in Ethiopia in general and in study area in particular. Therefore, this study was aimed to assess status of children’s adherence to ART and associated factors in study area. Methods- We conduct a facility-based cross-sectional study by including total of 282 children <15 years, who received Anti retro viral therapy for at least one month. All children/caregivers who were attending ART clinic during data collection period were consecutively recruited to the study. Both bivariate and multivariate logistic regression were performed. Result- Out of 282 caregivers included with their children, 226(80.2%) were females (mean age= 38.6 and SD = 12.35) and out of the total children, half (50%) were female and 246(87.2%) were between the ages 5–14 years (mean age= 8.5 and SD = 2.64). Two hundred forty six (87.2%) children had adherence status of ≥95% in the month prior to interview. Children whose caregivers were residing in urban were 3.3 (95% CI: 1.17, 9.63) times more adherent to ART than those whose caregivers were residing in rural. Children whose caregivers were biological parent were 2.37(95% CI: 1.59, 3.3) times more adherent than those whose caregivers were non biological parent. Also children of caregivers who were knowledgeable about ART treatment, were 4.5(95% CI: 1.79, 9.8) times more adherent to ART than their counter partsConclusion and recommendation- Adherence status of children in our study area was comparable. Being biological caregivers, residing in urban and knowledgeable about ART treatment were facilitate adherence to ART. Ongoing education about treatment and further study with multiple adherence assessment method were recommended.

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“…Studies study from Ethiopia, 14 Uganda, 10 North India, 13 and a study from Thailand 12 who have reported a higher level of adherence to ART which is 93.3%, 97.3%, 95.3%, and 98.8% of the respondents, respectively. Nevertheless, studies from South Wollo Zone Hospitals, Ethiopia, 3 Fiche Hospital, Ethiopia, 8 and Togo, West Africa 11 reported a lower level of adherence to ART among the children as 78.6%, 64.2%, and 58%, respectively. The difference might be due to fully subsidize, experience on side effects of treatments, differences in the measurement of adherence assessment used, socio-demographic and cultural background of study participants, and the difference of patient-healthcare provider relationships in different settings.…”

Section: Discussionmentioning

confidence: 98%

“…This is in line with the study in Fiche Hospital, Ethiopia, which reported caregivers of children with higher education were less likely to be non-adherent than the non-educated caregivers. 8 …”

Section: Discussionmentioning

confidence: 99%

Adherence to Antiretroviral Therapy and Associated Factors Among HIV-Infected Children in Public Health Institutions of Adwa, Axum, and Shire Towns of Tigray, Northern Ethiopia: A Cross-Sectional Study

Tesfahunegn¹,

Berhe²,

Abraha³

et al. 2023

HIV

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Background Antiretroviral therapy (ART) provision was among the major challenge of treatments. Maintaining the optimal level of adherence among children living with HIV/AIDS is a pivotal step towards achieving treatment success. However, there are limited studies on child’s ART adherence. Therefore, this study aimed to assess the level of adherence to antiretroviral therapy and associated factors among HIV-infected children in health institutions of Adwa, Axum, and Shire towns, Tigray, Northern Ethiopia. Methods An institutional-based cross-sectional study was conducted among human immunodeficiency virus (HIV)-infected children in between February and April, 2016. A total of 255 children who were taking antiretroviral therapy in the randomly selected three health facilities from Adwa, Axum and Shire towns were included. Data were collected using pretested and structured questionnaires using a face-to-face interview. The collected data were entered into Epi Info version 7 and then exported to SPSS version 21 for analysis. Bivariate and multivariate binary logistic regression models were used to determine the factors associated with adherence to antiretroviral therapy among HIV-infected children. Results A total of the 255 study participants were included in the study. The level of ART adherence among HIV-positive children was 212 (84.8%). Knowledge of caregivers about ART treatment (AOR = 2.78, 95% CI: 1.18, 6.53), occupational status (AOR = 4.78, 95% CI: 1.26, 18.91), appointment to ART less than two months (AOR = 3.05, 95% CI: 1.21, 7.70) and use of memory aids (AOR = 4.58, 95% CI: 1.73, 12.13) were independently associated with adherence to ART. Conclusion The level of adherence to antiretroviral therapy was low. Healthcare providers should reinforce adherence intervention and counseling sessions during follow-up and address the proper use of medication reminders to help children take their drugs appropriately.

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Magnitude and Associated Factors of Non-Adherence to Highly Active Antiretroviral Therapy among Children in Fiche Hospital, North Shewa, Ethiopia, 2016

Cited by 4 publications

References 8 publications

Adherence to Antiretroviral Therapy and Associated Factors Among Children Living With HIV in East Wallaga Zone Public Health Institutions, Ethiopia

Adherence to Antiretroviral Therapy and Associated Factors Among Children Living With HIV in East Wallaga Zone Public Health Institutions, Ethiopia

Children’s Adherence to Antiretroviral Therapy and Associated Factors: Multi-center Cross-sectional Study

Adherence to Antiretroviral Therapy and Associated Factors Among HIV-Infected Children in Public Health Institutions of Adwa, Axum, and Shire Towns of Tigray, Northern Ethiopia: A Cross-Sectional Study

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