Magnification-corrected photodynamic therapy

Ansari-Shahrezaei, Siamak; Erdem, Ergün; Chong, Robert; Tufail, Adnan; Wedrich, Andreas; Stur, Michael

doi:10.1007/s00417-006-0419-y

Cited by 5 publications

(1 citation statement)

References 22 publications

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“…The extent of the PDT treatment spot inaccuracy regarding undersized or oversized treatment is dependent on the laser unit used, as shown, and the method of measuring the CNV lesion [16][17][18]. In order to overcome the aforementioned difficulties, already a method was presented for PDT with a constant predictable light fluence based on actual laser spot magnification [9,19].…”

Section: Discussionmentioning

confidence: 98%

The effect of laser unit on photodynamic therapy spot size

Ansari-Shahrezaei

Binder

Stur

2010

Graefes Arch Clin Exp Ophthalmol

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Section: Discussionmentioning

confidence: 98%

The effect of laser unit on photodynamic therapy spot size

Ansari-Shahrezaei

Binder

Stur

2010

Graefes Arch Clin Exp Ophthalmol

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Regenerative Retinal Laser and Light Therapies (RELITE): Proposal of a New Nomenclature, Categorization, and Trial Reporting Standard

von der Burchard,

Miura,

Stanzel

et al. 2024

Lasers Surg Med

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ObjectivesNumerous laser and light therapies have been developed to induce regenerative processes in the choroid/retinal pigment epithelium (RPE)/photoreceptor complex, leaving the neuroretina undamaged. These therapies are applied to the macula for the treatment of various diseases, most prominently diabetic maculopathy, retinal vein occlusion, central serous chorioretinopathy, and age‐related macular degeneration. However, the abundance of technologies, treatment patterns, and dosimetry protocols has made understanding these therapies and comparing different approaches increasingly complex and challenging. To address this, we propose a new nomenclature system with a clear categorization that will allow for better understanding and comparability between different laser and light modalities. We propose this nomenclature system as an open standard that may be adapted in future toward new technical developments or medical advancements.MethodsA systematic literature review of reported macular laser and light therapies was conducted. A categorization into a standardized system was proposed and discussed among experts and professionals in the field. This paper does not aim to assess, compare, or evaluate the efficacy of different laser or dosimetry techniques or treatment patterns.ResultsThe literature search yielded 194 papers describing laser techniques, 50 studies describing dosimetry, 272 studies with relevant clinical trials, and 82 reviews. Following the common therapeutic aim, we propose “regenerative retinal laser and light therapies (RELITE)” as the general header. We subdivided RELITE into four main categories that refer to the intended physical and biochemical effects of temperature increase (photothermal therapy, PTT), RPE regeneration (photomicrodisruption therapy, PMT), photochemical processes (photochemical therapy, PCT), and photobiomodulation (photobiomodulation therapy, PBT).Further, we categorized the different dosimetry approaches and treatment regimens. We propose the following nomenclature system that integrates the most important parameters to enable understanding and comparability:Pattern—Dosimetry—Exposure Time/Frequency, Duty Cycle/Irradiation Diameter/Wavelength—Subcategory—Category.ConclusionRegenerative retinal laser and light therapies are widely used for different diseases and may become valuable in the future. A precise nomenclature system and strict reporting standards are needed to allow for a better understanding, reproduceable and comparable clinical trials, and overall acceptance. We defined categories for a systematic therapeutic goal‐based nomenclature to facilitate future research in this field.

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Indikationen für photodynamische Therapie mit Verteporfin im Zeitalter der intravitrealen Therapie – eine Übersicht

Stur¹

2008

Spektrum Augenheilkd.

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Magnification-corrected photodynamic therapy

Cited by 5 publications

References 22 publications

The effect of laser unit on photodynamic therapy spot size

The effect of laser unit on photodynamic therapy spot size

Regenerative Retinal Laser and Light Therapies (RELITE): Proposal of a New Nomenclature, Categorization, and Trial Reporting Standard

Indikationen für photodynamische Therapie mit Verteporfin im Zeitalter der intravitrealen Therapie – eine Übersicht

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