Magnetostrictive bulk Fe-Ga alloys prepared by selective laser melting for biodegradable implant applications

Gao, Chengde; Zeng, Zihao; Peng, Shuping; Shuai, Cijun

doi:10.1016/j.matdes.2022.110861

Cited by 32 publications

(21 citation statements)

References 60 publications

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“…The scaffold not only needs a good antibacterial property but also should possess excellent tracheal regeneration function when it is applied to repair tracheal defects. − The proliferation and live/dead staining of mBMSCs after coculturing with the composite scaffolds under 808 nm NIR light irradiation for 15 min were employed to evaluate the effect of heating and ROS on the cells surrounding the scaffold. As shown in Figure a, on the first day of culture, the number of mBMSCs for the ZnCN-Bi 2 S 3 /PLLA group was lower than that of the PLLA group under NIR light irradiation for 15 min, and more dead cells cultured on the ZnCN-Bi 2 S 3 /PLLA with NIR light irradiation were observed than for the PLLA group under 808 nm NIR light irradiation, indicating that the heating and ROS produced by the photothermal and photodynamic effects could hurt normal cells in some scaffolds.…”

Section: Resultsmentioning

confidence: 99%

Photothermal and Photodynamic Effects of g-C₃N₄ Nanosheet/Bi₂S₃ Nanorod Composites with Antibacterial Activity for Tracheal Injury Repair

Qian

Wen

Shuai

et al. 2022

ACS Appl. Nano Mater.

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Photodynamic antimicrobial therapy via producing ROS based on light-responsive nanoparticles has attracted worldwide attention because of the high selectivity and low side effects. However, biofilms and bacterial membranes provide a natural barrier to prevent the penetration of ROS, which impairs the photodynamic antibacterial efficiency of nanoparticles. Photothermal therapy is an effective strategy against biofilms and bacterial membranes because high temperature can destroy the biofilm structure and enhance the membrane permeability. Herein, Bi2S3 nanorods were anchored on the surface of zinc-doped g-C3N4 (ZnCN) nanosheets to construct a ZnCN-Bi2S3 nanocomposite; then, it was incorporated into poly-l-lactic acid and prepared into scaffolds by the selective laser sintering technology. Bi2S3 nanorods not only endowed the scaffold with an excellent photothermal property but also strengthened the photodynamic effect of ZnCN nanosheets after forming the nanocomposite. The results showed that this nanocomposite had a lower recombination rate of photogenerated electron–hole pairs and produced higher photocurrent compared to those of the g-C3N4 nanosheets and Bi2S3 nanorods. The scaffold destroyed the biofilm and elevated the bacterial membrane permeability significantly and finally achieved 98.5% antibacterial rate for Staphylococcus aureus and 96.3% antibacterial rate for Pseudomonas aeruginosa. Encouragingly, the scaffold could also promote chondrogenic differentiation because of the continuous release of Zn ions. The scaffold containing ZnCN-Bi2S3 nanocomposites possessed excellent antimicrobial and cartilage regeneration functions, which displayed great potential in treating tracheal injuries.

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Section: Resultsmentioning

confidence: 99%

Photothermal and Photodynamic Effects of g-C₃N₄ Nanosheet/Bi₂S₃ Nanorod Composites with Antibacterial Activity for Tracheal Injury Repair

Qian

Wen

Shuai

et al. 2022

ACS Appl. Nano Mater.

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“…Biometals, including stainless steel and titanium alloy, possess distinguished mechanical properties and plastic toughness, and they can cause some complications and the release of toxic metal ions easily, and so on. [13][14][15][16][17] Bioceramics, including hydroxyapatite (HAP) and tricalcium phosphate (TCP), have great bioactivity, biocompatibility, and bone conductivity, but the major issue is their poor strength and low toughness. [18][19][20] Biopolymers, including poly (L-lactide) (PLLA) and poly (ε-caprolactone) (PCL), possess good biosafety, biodegradability, and formability, but their strength is insufficient, and their degradation products are acidic, easily resulting in aseptic inflammatory reaction.…”

Section: Introductionmentioning

confidence: 99%

Structural and Functional Adaptive Artificial Bone: Materials, Fabrications, and Properties

Feng

Zhao

Tang

et al. 2023

Adv Funct Materials

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It is an urgent need that defect repair can develop from simple device fixation to living tissue reconstruction, from short life function replacement to permanent regeneration repair. At present, bone transplantation has become the second largest transplantation surgery after blood transfusion, and artificial bone transplantation generates great hope for the repair and treatment of bone defect. In order to repair bone defect, artificial bone must have good biological properties and sufficient mechanical properties, and it should also have the shape matching to bone defect site and the connected porous structure. For structures and properties requirements of artificial bone, in this review three major challenges faced by artificial bone transplantation are systemtically analyzed and current methods and strategies to address these issues are discussed: 1) the need for developing a type of bone scaffold material with both biological and mechanical properties, 2) the need for realizing the controllable fabrication of individual shape and multistage pore structure of bone scaffold, 3) the need for realizing the transformation from man‐made structure to biological structure. Besides, it summarizes the advantages and disadvantages of these methods and discusses the potential future directions of structural and functional adaptive artificial bone for bone defect regeneration.

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“…Moreover, researchers are becoming increasingly interested in Fe-Ga alloys as magnetostrictive materials for biomedical applications owing to their good mechanical properties and low magnetic hysteresis. [30] Magnetostrictive alloys exhibit reversible deformation in external magnetic fields and are prospected with a focus on their potential applications in bone repair. [30] This review focuses on summarizing various metal and alloy materials that can serve as implants for bone repair, including traditional metal materials such as stainless steels [31] and Ti alloys [32] biodegradable alloys such as Fe-based, [33] , Mgbased, [34] and Zn-based alloys; [35] and novel metal materials such as Ta metal, [36,37] Bi-based alloys, [29,38] and magnetostrictive Fe-Ga alloys [30] (Figure 1).…”

Section: Introductionmentioning

confidence: 99%

Metallic Materials for Bone Repair

Fan,

Chen,

Yang

et al. 2023

Adv Healthcare Materials

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Repair of large bone defects caused by trauma or disease poses significant clinical challenges. Extensive research has focused on metallic materials for bone repair because of their favorable mechanical properties, biocompatibility, and manufacturing processes. Traditional metallic materials, such as stainless steel and titanium alloys, are widely used in clinics. Biodegradable metallic materials, such as iron, magnesium, and zinc alloys, are promising candidates for bone repair because of their ability to degrade over time. Emerging metallic materials, such as porous tantalum and bismuth alloys, have gained attention as bone implants owing to their bone affinity and multifunctionality. However, these metallic materials encounter many practical difficulties that require urgent improvement. In this article, we systematically reviewed and analyzed the metallic materials used for bone repair, providing a comprehensive overview of their morphology, mechanical properties, biocompatibility, and in vivo implantation. Furthermore, we summarized the strategies and efforts made to address the short‐comings of metallic materials. Finally, we identified and discussed perspectives for the development of metallic materials to guide future research and advancements in clinical practice.This article is protected by copyright. All rights reserved

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Magnetostrictive bulk Fe-Ga alloys prepared by selective laser melting for biodegradable implant applications

Cited by 32 publications

References 60 publications

Photothermal and Photodynamic Effects of g-C₃N₄ Nanosheet/Bi₂S₃ Nanorod Composites with Antibacterial Activity for Tracheal Injury Repair

Photothermal and Photodynamic Effects of g-C₃N₄ Nanosheet/Bi₂S₃ Nanorod Composites with Antibacterial Activity for Tracheal Injury Repair

Structural and Functional Adaptive Artificial Bone: Materials, Fabrications, and Properties

Metallic Materials for Bone Repair

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Magnetostrictive bulk Fe-Ga alloys prepared by selective laser melting for biodegradable implant applications

Cited by 32 publications

References 60 publications

Photothermal and Photodynamic Effects of g-C3N4 Nanosheet/Bi2S3 Nanorod Composites with Antibacterial Activity for Tracheal Injury Repair

Photothermal and Photodynamic Effects of g-C3N4 Nanosheet/Bi2S3 Nanorod Composites with Antibacterial Activity for Tracheal Injury Repair

Structural and Functional Adaptive Artificial Bone: Materials, Fabrications, and Properties

Metallic Materials for Bone Repair

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Product

Resources

About

Photothermal and Photodynamic Effects of g-C₃N₄ Nanosheet/Bi₂S₃ Nanorod Composites with Antibacterial Activity for Tracheal Injury Repair

Photothermal and Photodynamic Effects of g-C₃N₄ Nanosheet/Bi₂S₃ Nanorod Composites with Antibacterial Activity for Tracheal Injury Repair