This paper aims to contribute to the stratigraphic and geochronological knowledge of the Neogene-Quaternary of the geologic province of Tandilia by doing lithostratigraphic, paleomagnetic and paleontological analyses. Four lithostratigraphic units have been recognized. The oldest (Late Miocene) constitutes a unit composed of colluvium deposits; it lays in erosional unconformity over the Neoproterozoic rocks. This unconformity is related to important events in the Andes during the Middle-Late Miocene. Over the oldest colluvial sediments, and placed in erosional unconformity, there are sediments assigned to the Barker Formation which are essentially fluvial deposits with a development of several paleosols. Owing to the fossil remains, this unit is assigned to the Montehermosan-Chapadmalalan Stage/Age, whereas the paleomagnetic record would correspond to C3A, Gilbert and Gauss chrons. So, the age is narrowed to the timespan 7.1-3.1 Ma (Late Miocene-Early Pliocene). The Vela Formation lays in erosional unconformity over the Barker Formation. It also has fluvial origin, while the youngest unit (Las Á nimas Formation) corresponds to loess. Both units provide normal polarity and were assigned to Brunhes chron (\0.78 Ma). The Vela Formation presents fossil remains from Bonaerian-Lujanian Stage/Age and belongs to the Middle Pleistocene. The hiatus between the Barker and Vela Formations seems to be considerable: it represents at least 2.6 million years. The reason for the lack of sedimentary records is still a matter of discussion. The deposition of Las Animas Formation seems to span the last 40,000 years. However, this could be linked to a major entrance of windcarried sediments during dry periods, including the Last Glacial Maximum. The hiatus between the Vela and Las Á nimas Formations may have been over 100,000 years.