Magnetooptical characterization of human blood serum: correlation between neoplasmic changes and their biomolecular information carriers

Surma, M.

doi:10.1080/00319100600620912

Cited by 5 publications

(7 citation statements)

References 10 publications

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“…The possibility of differentiation between the cancer and non-cancer states on the basis of the magneto-optical results has been tested [2]. The MOCB data collected suggest that the blood serum of cancer patient contains a stable bio-molecular structure.…”

Section: Introductionmentioning

confidence: 99%

Cancer Status: Mocb and tPSA Prostate Cancer Markers

Surma¹

2012

JCT

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On the basis of the results of magneto-optical studies and their comparison with the outcome of medical tests magneto-optical MOCB and tPSA serum markers of cancer/recovered patient are presented. Status of the cancer serum donor is recognized as presence of the laevorotatory optical active molecules of (−) ρ density in serum while status of the recovered donor is recognized as quantitative domination of the dextrorotatory (+) ρ molecules in serum. These molecular information carriers (−) ρ and (+) ρ are recorded by the magneto-optical circular birefringence MOCB effect in B 2 magnetic field. The laevo/dextrorotatory carriers are enantiomers in the case of (−) ρ = (+) ρ relations fulfilled for any individual cancer and the same recovered patient. The positive predictive value PPV of MOCB results is 100%.

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Section: Introductionmentioning

confidence: 99%

Cancer Status: Mocb and tPSA Prostate Cancer Markers

Surma¹

2012

JCT

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“…Comparison of the results of MOCB molecular marker and tPSA protein marker are given in Tables 1-3. MOCB, b exp < 0, the measurements for the serum from prostate patients (1,2,3,4) indicates the presence of cancer and tPSA > 4 ng/mL indicates the presence of cancer. For patients (1,2,3,4) the results obtained by the two methods MOCB and protein markers are fully consistent: b exp < 0, tPSA > 4 ng/mL. Disagreement of Mocb with tPSA data: Table 1 (5), b exp < 0, tPSA < 4 ng/mL.…”

Section: Resultsmentioning

confidence: 99%

“…Protein markers provide information on the cancer disease status but with a large margin of error, the information is often unreliable for evaluation of the actual status of disease development and effectiveness of the therapy applied. As shown in paper [1], reliable information is provided by the magnetic field B 2 induced angle of rotation b exp of the polarisation plane of light passing through the serum from the blood of the patient. The human blood serum in a magnetic field B 2 becomes optically birefringent (Magnetooptical Circular Birefringence).…”

Section: Introductionmentioning

confidence: 99%

Molecular Marker of Tumours

Surma¹

2016

JCT

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Molecular structure of the marker of tumour is determined by magneto-optical analysis of blood serum. The marker is the laevorotatory enantiomer of alanine. The cancer status of a subject is described by the number of molecules of the laevorotatory alanine enantiomer (−) ρ and the effectiveness of therapy is measured by the number of molecules of the dextrorotatory alanine enantiomer (+) ρ. The values of (−) ρ and (+) ρ are determined separately for the patient before and after therapy.

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“…It has been established and summarized [1] that measurements of magneto-optical birefringence in the human blood serum bring information on the cancer status of the patient. This paper is based on the Magneto Optical Circular Birefringence MOCB results published although in this paper they are analysed in an aspect of enantiomers electric quadrupole and magnetic dipolar molecules present in serum of cancer, cancer recovered [2] patient.…”

Section: Introductionmentioning

confidence: 99%

“…That has been firstly signalled and implied in [1] [2]. Physical technique of the method is measurement of the serum optical birefringence.…”

Section: Introductionmentioning

confidence: 99%

Enantiomers Present in Serum Carry Cancer and/or Recovery Status Information

Surma¹

2014

JCT

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Human blood serum of cancer, cancer-recovered and healthy patients contains laevorotatory and dextrorotatory B 2 active molecules. The laevorotatory B 2 active carriers in patient serum carry information on the cancer status while the dextrorotatory B 2 active carriers carry information on the recovered and/or healthy patient status. Their magneto-optical characteristic is analysed by the B 2 Magneto Optical Circular Birefringence. By applying the MOCB experimental technique, it is possible to differentiate between the cancer and non-cancer patients. The paper introduces a purely molecular physics approach for description of the cancer/recovered and also non-cancer patients status.

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Magnetooptical characterization of human blood serum: correlation between neoplasmic changes and their biomolecular information carriers

Cited by 5 publications

References 10 publications

Cancer Status: Mocb and tPSA Prostate Cancer Markers

Cancer Status: Mocb and tPSA Prostate Cancer Markers

Molecular Marker of Tumours

Enantiomers Present in Serum Carry Cancer and/or Recovery Status Information

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