Magneto-optical FeGa2O4 nanoparticles as dual-modality high contrast efficacy T2 imaging and cathodoluminescent agents

Abstract

The magneto-optical FeGa(2)O(4) nanoparticles with high Fe mass magnetization exhibited a high-performance T(2)-lowering effect and displayed cathodoluminescence.

Morphological, structural and magnetic evolution of sputtered Fe70Ga30 thin films upon annealing in oxygen atmosphere

“…Some of these alloys with a composition around FeGaO 3 are piezoelectric with an additional large linear magnetoelectric effect [12]. Other oxides close to the FeGa 2 O 4 composition have been proposed for hyperthermia treatments and as the insulating paramagnetic layer in a magnetic tunnel junction [13][14][15]. There are works devoted to the properties of bulk samples [1, 2 , 3, 11-12, 16], to thin films and nanoparticles [4-7, 9, 14-15 17-18].…”

Towards the design of contrast-enhanced agents: systematic Ga3+ doping on magnetite nanoparticles

“…28 However, other studies demonstrate the random distribution of Ga 3+ between the tetrahedral and octahedral positions, which would also result in a nonlinear evolution of the cell parameters with gallium content. 40,41 Regarding the morphological analysis of the samples, transmission electron microscopy (TEM) showed similar morphologies (cuboctahedrons) and sizes in the 6-12 nm range, as can be seen in Fig. 2.…”

“…All the analysed samples have shown considerable high r 1 and r 2 values, which are above the relaxivities observed for commercial contrast agents (commercial AMI-227, SHU-555C (r 1 = 2.9 mM −1 s −1 , r 2 = 69 mM −1 s −1 ) or for gallium ferrite nanoparticles or other synthesized magnetite nanoparticles of similar sizes. 22 Contrast agents are usually classified according to their relationship of relaxation; therefore, if materials show a high r 2 /r 1 ratio they are classified as T 2 contrast agents, enhancing the dark contrast and when the r 1 values are high and the r 2 /r 1 ratio is close to 1, T 1 contrast agents are obtained. 65 In our case, different relaxation values were obtained depending on the gallium content.…”

“…21 In this sense, gallium ferrites have aroused great interest not only due to the possibility of their use in diagnosis as contrast nanomaterials in MRI or as radiopharmaceuticals but also in medical therapies such as magnetic hyperthermia. 22,23 It is to be noted that despite the traditional applications of gallium-doped ferrites for their magnetoelectrical properties, gallium presents many biological effects in the treatment of bone metastases, Paget′s disease, postmenopausal osteoporosis or in some lymphomas. 24,25 All this potentiality in biomedicine has lavished the preparation and characterization of gallium ferrites with different compositions with the aim of tailoring their properties.…”

Opto-Magnetic Method for Epstein - Barr Virus and Cytomegalovirus Detection in Blood Plasma Samples

“…Similar methodology uses method that is an inverse of opto-magnetism, or magneto-optical method, and has examined percentage of iron in an alloy [11].…”