Magnetite‐doped electrospun fibers forDNAadsorption

Abstract

Gene delivery, biosensing-based diagnostic therapy, and in vivo responsive drugs are promising technologies based on the interaction of DNA with supports on the nanoscale. Typical advantages for nanomaterials applied in DNA removal are related to their high surface area and availability of cationic sites that favor the electrostatic interaction with the target (DNA). Herein, a magnetite-doped cationic polymer was explored as a support for the production of electrospun fibers that offer an abundance of the available sites for the adsorption of DNA while exploring the doping effect of magnetite for the improvement in the adsorption capacity and the magnetic removal from the reactor. The mechanisms of adsorption revealed that the Freundlich isotherm prevails in a process denoted by the pseudo-second-order kinetic model.