Magnetically separable triazine-based Cu(ii)–vitamin B₅ complex in nitromethane toward efficient heterogeneous cyanation reaction of aryl halides

Abstract

An efficient heterogeneous copper catalyst was developed by supporting copper acetate on magnetically separable triazine–vitamin B5. Its catalytic efficiency was evaluated in the cyanation of aryl halides with nitromethane as a non-toxic and cost-effective cyanating source.

Synthesis and characterization of a green and recyclable arginine-based palladium/CoFe2O4 nanomagnetic catalyst for efficient cyanation of aryl halides

“…In addition, a comparison of reaction efficiencies between aryl iodides and aryl bromides reveals the former's superiority, attributed to the weaker C–I bond in contrast to the C–Br bond. 14,27…”

“…In addition, a comparison of reaction efficiencies between aryl iodides and aryl bromides reveals the former's superiority, attributed to the weaker C-I bond in contrast to the C-Br bond. 14,27 Additionally, in the utilization of the Pd/CoFe 2 O 4 @ACT nanoparticles, it was observed that electron-rich or electron-decient substitutions were not pivotal factors affecting product yields. Furthermore, analysis from Table 8 indicates that aryl halides with O-substitution (2d and 2h) yielded lower results than their counterparts with P-substitution (2b and 2e), suggesting a hindrance effect as a contributing factor.…”

“…To overcome this problem, several less-toxic metal-free cyanide sources including malononitrile, butyronitrile, acetonitrile, and benzyl cyanide have been reported. 27,28 Aryl halide cyanations have been reported in various publications utilizing various Pd catalysts, including Pd/C, Pd complexes, and Pd(OAc) 2 . [29][30][31][32] However, the main limitations of these catalysts are their recovery and reuse.…”