Magnetically-enabled biomarker extraction and delivery system: towards integrated ASSURED diagnostic tools

Bauer, Westley S.; Kimmel, Danielle W.; Adams, Nicholas M.; Gibson, Lauren E.; Scherr, Thomas; Richardson, Kelly A.; Conrad, Joseph A.; Matakala, Hellen K.; Haselton, Frederick R.; Wright, David W.

doi:10.1039/c7an00278e

Cited by 12 publications

(15 citation statements)

References 47 publications

(54 reference statements)

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“…A device that fully integrates sample preparation step the lateral flow assay, similar to those developed by Ricks et al and Bauer et al, could fill the need to further simplify CAA concentration at the point of care. 33,34 Finally, PAMAM-functionalization of paper membranes (e.g. cellulose) could open the door to paper fluidic devices that combine the advantages of sample preparation and sensitive detection into a single, affordable, and integrated device applicable in a field setting.…”

Section: Discussionmentioning

confidence: 99%

Poly(amidoamine)-coated magnetic particles for enhanced detection ofSchistosomacirculating anodic antigen in endemic urine samples

Markwalter

Corstjens

Mammoser

et al. 2019

Analyst

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Section: Discussionmentioning

confidence: 99%

Poly(amidoamine)-coated magnetic particles for enhanced detection ofSchistosomacirculating anodic antigen in endemic urine samples

Markwalter

Corstjens

Mammoser

et al. 2019

Analyst

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“…Laboratory diagnosis is not feasible in resource-limited settings, including many dengue-endemic regions. The POC diagnosis test must fulfill WHO's ASSURED criteria that summarize affordable, sensitive, specific, user-friendly, rapid and robust, equipment-free, and deliverable to those in need (Bauer et al, 2017;Jacobsson et al, 2018). The necessity for quick and miniaturized POC tests for dengue virus detection has created many methods as an alternative to heavy lab instruments.…”

Section: Future Perspectives and Electrical Biosensors Technologiesmentioning

confidence: 99%

Dengue virus infection: A review of advances in the emerging rapid detection methods

Hussain¹,

Ali²,

Liu³

et al. 2022

Biocell

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Dengue virus infections are increasing worldwide generally and in Asia, Central and South America and Africa, particularly. It poses a serious threat to the children population. The rapid and accurate diagnostic systems are essentially required due to lack of effective vaccine against dengue virus and the progressive spread of the dengue virus infection. The recent progress in developing micro-and nano-fabrication techniques has led to low cost and scale down the biomedical point-of-care devices. Starting from the conventional and modern available methods for the diagnosis of dengue infection, this review examines several emerging rapid and point-of-care diagnostic devices that hold significant potential for the progress in smart diagnosis tools. The given review revealed that an effective vaccine is required urgently against all the dengue virus serotypes. However, the rapid detection methods of dengue virus help in early treatment and significantly reduce the dengue virus outbreak.

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Section: Metal-based Sample Preparationmentioning

confidence: 99%

Inorganic Complexes and Metal-Based Nanomaterials for Infectious Disease Diagnostics

et al. 2018

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Infectious diseases claim millions of lives each year. Robust and accurate diagnostics are essential tools for identifying those who are at risk and in need of treatment in low-resource settings. Inorganic complexes and metal-based nanomaterials continue to drive the development of diagnostic platforms and strategies that enable infectious disease detection in low-resource settings. In this review, we highlight works from the past 20 years in which inorganic chemistry and nanotechnology were implemented in each of the core components that make up a diagnostic test. First, we present how inorganic biomarkers and their properties are leveraged for infectious disease detection. In the following section, we detail metal-based technologies that have been employed for sample preparation and biomarker isolation from sample matrices. We then describe how inorganic- and nanomaterial-based probes have been utilized in point-of-care diagnostics for signal generation. The following section discusses instrumentation for signal readout in resource-limited settings. Next, we highlight the detection of nucleic acids at the point of care as an emerging application of inorganic chemistry. Lastly, we consider the challenges that remain for translation of the aforementioned diagnostic platforms to low-resource settings.

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Magnetically-enabled biomarker extraction and delivery system: towards integrated ASSURED diagnostic tools

Cited by 12 publications

References 47 publications

Poly(amidoamine)-coated magnetic particles for enhanced detection ofSchistosomacirculating anodic antigen in endemic urine samples

Poly(amidoamine)-coated magnetic particles for enhanced detection ofSchistosomacirculating anodic antigen in endemic urine samples

Dengue virus infection: A review of advances in the emerging rapid detection methods

Inorganic Complexes and Metal-Based Nanomaterials for Infectious Disease Diagnostics

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