Magnetic Wire Traps and Programmable Manipulation of Biological Cells

Vieira, G.; Henighan, Thomas; Chen, A.; Hauser, Adam J.; Yang, Fengyuan; Chalmers, J. J.; Sooryakumar, R.

doi:10.1103/physrevlett.103.128101

Cited by 107 publications

(99 citation statements)

References 29 publications

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“…Once the bead is trapped in the potential well of the DW, the DW can be used to manipulate individual beads. Indeed, bead transport has been realized by either stepping a bead from one DW trap site to the next 19,[21][22][23][24]27 or moving it continuously with a propagating DW 20,22,25,26 . Continuous transport is limited, however, by the maximum interaction force, or binding force , between the bead and DW, which must overcome the hydrodynamic drag force on the bead as it is pulled through the host fluid 20 .…”

Section: Magnetic Bead-dw Interactionmentioning

confidence: 99%

“…Although several estimates of the binding strength between a wall and trapped bead have been reported 19,20,23,24,27 , these calculations have generally been limited to model parameters which do not accurately represent the size and magnetic state of the bead-DW system. In this work, we use a combination of micromagnetic modeling and numerical calculation to predict bead-DW interaction forces for experimentally relevant geometries.…”

Section: Introductionmentioning

confidence: 99%

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Transport dynamics of superparamagnetic microbeads trapped by mobile magnetic domain walls

Rapoport

Beach

2013

Phys. Rev. B

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The dynamics of fluid-borne superparamagnetic bead transport by field-driven domain walls in submicrometer ferromagnetic tracks is studied experimentally together with numerical and analytical modeling. A combination of micromagnetic modeling and numerical calculation is used to determine the strength of bead-domain wall interaction for a range of track geometries and bead sizes. The maximum domain wall velocity for continuous bead transport is predicted from these results and shown to be supported by experimental measurements. Enhancement of the maximum velocity by appropriate material selection or field application is demonstrated and an analysis of the source of statistical variation is presented. Finally, the dynamics of beaddomain wall interaction and bead transport above the maximum domain wall velocity for continuous domain wall-mediated bead transport is characterized.Submitted to Phys. Rev. B 2

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Section: Magnetic Bead-dw Interactionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Transport dynamics of superparamagnetic microbeads trapped by mobile magnetic domain walls

Rapoport

Beach

2013

Phys. Rev. B

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“…This has recently been exploited by devices that manipulate beads using stray fields from localized field sources such as closure domains of patterned elements 4,10,11 or domain walls in nanowires. 5,6,12,13 If the beads are attached to cells, the use of nanostructures enables the alignment or pattering of cells, 6 providing a fundamental control over cellular organization, which could generate future tissue engineering applications. In addition, domain walls may be propagated using applied magnetic fields or spin-polarized currents, so biological material attached to the beads can be translated over a pre-defined path.…”

mentioning

confidence: 99%

“…Superparamagnetic beads are widely used within bioscience to separate, organize and manipulate biomolecules and cells, [1][2][3][4][5][6] and have promising clinical applications as they can be used as MRI contrast agents and in magnetic hyperthermia for the treatment of cancer. 7,8 Typically, they consist of iron oxide (Fe 2 O 3 or Fe 3 O 4 ) nanoparticles embedded in a polymer matrix, which may have an outer coating functionalized for a particular biological application.…”

mentioning

confidence: 99%

The effect of trapping superparamagnetic beads on domain wall motion

Bryan

Dean

Schrefl

et al. 2010

Applied Physics Letters

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Domain walls may act as localized field sources to trap and move superparamagnetic beads for manipulating biological cells and DNA. The interaction between beads of various diameters and a wall is investigated using a combination of micromagnetic and analytical models. Domain walls can transport beads under applied magnetic fields, but the mutual attraction between the bead and wall causes drag forces affecting the bead to couple into the wall motion. Therefore, the interaction with the bead causes a fundamental change in the domain wall dynamics, reducing the wall mobility by five orders of magnitude.

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“…[6][7][8] The viability of DW-based spintronic technologies rests largely on how fast DWs can be propelled in nanoscale structures. It has recently been experimentally demonstrated 9 that DWs driven by moderate strength longitudinal magnetic fields along a ferromagnetic nanowire obey a "speed limit.…”

Section: Introductionmentioning

confidence: 99%

Magnetic domain-wall velocity enhancement induced by a transverse magnetic field

Yang

Beach

Knutson

et al. 2016

Journal of Magnetism and Magnetic Materials

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Spin dynamics of field-driven domain walls (DWs) guided by Permalloy nanowires are studied by high-speed magneto-optic polarimetry and numerical simulations. DW velocities and spin configurations are determined as functions of longitudinal drive field, transverse bias field, and nanowire width. Nanowires having cross-sectional dimensions large enough to support vortex wall structures exhibit regions of drive-field strength (at zero bias field) that have enhanced DW velocity resulting from coupled vortex structures that suppress oscillatory motion. Factor of ten enhancements of the DW velocity are observed above the critical longitudinal drive-field (that marks the onset of oscillatory DW motion) when a transverse bias field is applied. Nanowires having smaller cross-sectional dimensions that support transverse wall structures also exhibit a region of higher mobility above the critical field, and similar transverse-field induced velocity enhancement but with a smaller enhancement factor. The bias-field enhancement of DW velocity is explained by numerical simulations of the spin distribution and dynamics within the propagating DW that reveal dynamic stabilization of coupled vortex structures and suppression of oscillatory motion in the nanowire conduit resulting in uniform DW motion at high speed.

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Magnetic Wire Traps and Programmable Manipulation of Biological Cells

Cited by 107 publications

References 29 publications

Transport dynamics of superparamagnetic microbeads trapped by mobile magnetic domain walls

Transport dynamics of superparamagnetic microbeads trapped by mobile magnetic domain walls

The effect of trapping superparamagnetic beads on domain wall motion

Magnetic domain-wall velocity enhancement induced by a transverse magnetic field

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