Magnetic solid phase extraction based on phenyl silica adsorbent for the determination of tetracyclines in milk samples by capillary electrophoresis

Importance of Treatment Process on the Analysis of Penicillins in Milk Samples by Capillary Electrophoresis

“…This technique has demonstrated several advantages such as the decrease in sample treatment time, the decrease in solvent use, and the easy treatment of high volume samples [21][22]. The basic procedure involved in MSPE is represented in Figure 2.…”

“…MSPE-CE has been applied for the selective separation of tetracyclines and fluoroquinolones from milk samples. The possibility of modification has allowed the synthesis of magnetic solid modified with phenyl and phenyl-octyl in order to improve the selectivity during the sample treatment through mixed interaction modes [22][23].…”

Current Developments and Future Trends in Solid-phase Microextraction Techniques for Pharmaceutical and Biomedical Analyses

“…Furthermore, temperature-response 151 and light-response polymers and polymer-coated magnetic particles [152][153][154] may be useful as an intelligent polymer device for selective sample preparation. One of the main practical obstacles to SPME implementation to date has been the lack of commercial devices with appropriate characteristics, such as biocompatibility and good inter-fiber precision, for this type of application.…”

Dispersive solid-phase extraction based on butylamide silica for the determination of sulfamethoxazole in milk samples by capillary electrophoresis

“…The mixture was refluxed for 16 h with stirring. [25] Silica phase was then washed with distilled water, followed by ethanol (3 � 10 mL each one), and dried at 100°C for 24 h. In order to activate it, the silica (3.0 g) was immersed in 40 mL of HCl 3 M and refluxed for 8 h; later it was filtered, washed with distilled water, and dried at 120°C all night. Activated silica was mixed with 30 mL of anhydrous toluene, 0.5 mL of triethylamine, and 3 mL of APTMS; the mixture was refluxed for 24 h. Propylamine functionalized silica was filtered, washed with toluene followed by ethanol (3 � 10 mL each one), and dried at 60°C for 24 h. Concluded the reaction time, propylamine functionalized silica was mixed with 60 mL of methyl acrylate/methanol solution (1:1, v/v) and stirred under a nitrogen atmosphere at 50°C for 2 h. The product was filtered and washed with methanol to obtain methylester functionalized silica.…”