2024
DOI: 10.1002/ange.202318870
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Magnetic Silica‐Coated Fluorescent Microspheres (MagSiGlow) for Simultaneous Detection of Tumor‐Associated Proteins

Elias A. Halabi,
Isabel Gessner,
Katherine S. Yang
et al.

Abstract: Multiplexed bead assays for solution‐phase biosensing often encounter cross‐over reactions during signal amplification, leading to false positives and high background signals. Current solutions involve complex, custom‐designed equipment or costly setups, limiting their application in simple laboratory environments. In this study, we introduce a straightforward protocol to adapt a multiplexed single‐bead assay to standard fluorescence imaging plates, enabling the simultaneous analysis of thousands of reactions … Show more

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