Magnetic Resonance Imaging Prostate Volumes Could be Used as a Surrogate for Transrectal Ultrasound Volumes in Estimating Iodine-125 Seeds Required in Brachytherapy

Cheah, N.L.C.; Michaelides, Doros N.; Kong, Pengfei; Wyatt, Ruth; El-Modir, Ahmed

doi:10.1016/j.clon.2008.10.007

Cited by 3 publications

(4 citation statements)

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“…While previous studies of volume estimation in brachytherapy candidates have shown smaller differences between TRUS and MRI-based estimations than our findings [ 7 – 9 ], most studies have compared TRUS to contoured MRI, which is less clinically practical than using an ellipsoid estimation of volume on MRI. The one study to compare volumes derived from contouring on TRUS with ellipsoid MRI volumes in 15 patients who were not receiving hormone therapy found a correlation between volumes of r = 0.83 [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

Variability in MRI vs. ultrasound measures of prostate volume and its impact on treatment recommendations for favorable-risk prostate cancer patients: a case series

et al. 2014

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BackgroundProstate volume can affect whether patients qualify for brachytherapy (desired size ≥20 mL and ≤60 mL) and/or active surveillance (desired PSA density ≤0.15 for very low risk disease). This study examines variability in prostate volume measurements depending on imaging modality used (ultrasound versus MRI) and volume calculation technique (contouring versus ellipsoid) and quantifies the impact of this variability on treatment recommendations for men with favorable-risk prostate cancer.MethodsWe examined 70 patients who presented consecutively for consideration of brachytherapy for favorable-risk prostate cancer who had volume estimates by three methods: contoured axial ultrasound slices, ultrasound ellipsoid (height × width × length × 0.523) calculation, and endorectal coil MRI (erMRI) ellipsoid calculation.ResultsAverage gland size by the contoured ultrasound, ellipsoid ultrasound, and erMRI methods were 33.99, 37.16, and 39.62 mLs, respectively. All pairwise comparisons between methods were statistically significant (all p < 0.015). Of the 66 patients who volumetrically qualified for brachytherapy on ellipsoid ultrasound measures, 22 (33.33%) did not qualify on ellipsoid erMRI or contoured ultrasound measures. 38 patients (54.28%) had PSA density ≤0.15 ng/dl as calculated using ellipsoid ultrasound volumes, compared to 34 (48.57%) and 38 patients (54.28%) using contoured ultrasound and ellipsoid erMRI volumes, respectively.ConclusionsThe ultrasound ellipsoid and erMRI ellipsoid methods appeared to overestimate ultrasound contoured volume by an average of 9.34% and 16.57% respectively. 33.33% of those who qualified for brachytherapy based on ellipsoid ultrasound volume would be disqualified based on ultrasound contoured and/or erMRI ellipsoid volume. As treatment recommendations increasingly rely on estimates of prostate size, clinicians must consider method of volume estimation.

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Section: Discussionmentioning

confidence: 99%

Variability in MRI vs. ultrasound measures of prostate volume and its impact on treatment recommendations for favorable-risk prostate cancer patients: a case series

et al. 2014

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“…The accurate determination of prostatic volume is important in determining the degree of hyperplastic enlargement, the resultant tendency toward urinary‐tract outflow obstruction, and the preferred surgical treatment option. It is also important in determining which prostatic cancer patients are suitable for brachytherapy, as prostates with volumes above 50 mL are usually excluded . Whilst other non‐ionising imaging methods such as magnetic resonance imaging (MRI) are expensive and not readily available, others such as digital rectal examination (DRE) are inadequate for prostate size determination, and produce inaccurate measurements with increasing prostate sizes .…”

Section: Introductionmentioning

confidence: 99%

“…It is also important in determining which prostatic cancer patients are suitable for brachytherapy, as prostates with volumes above 50 mL are usually excluded . Whilst other non‐ionising imaging methods such as magnetic resonance imaging (MRI) are expensive and not readily available, others such as digital rectal examination (DRE) are inadequate for prostate size determination, and produce inaccurate measurements with increasing prostate sizes . Prostate‐specific antigen density has been found to be a significant predictor of adverse pathological features and recurrence in prostate cancer.…”

Section: Introductionmentioning

confidence: 99%

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Prostatic volume determination by transabdominal ultrasonography: Does accuracy vary significantly with urinary bladder volumes between 50 to 400 mL?

Brakohiapa

Botwe

Sarkodie

2019

J of Medical Radiation Sci

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Introduction In Ghana, trans‐abdominal ultrasonography is the main sonographic method of prostatic volume evaluation. The examinations are done when the patient's bladder is full. However, the delay and the discomforting experiences associated with a full bladder have been well documented. In an attempt to investigate other less discomforting options, this study was undertaken to determine if sonographic transabdominal prostatic evaluations performed at urinary bladder volumes of 50–99 mL differ significantly to evaluations done at volumes of 100–199, 200–299 and 300–399 mL. Methods A prostatic study of adult patients was undertaken in Accra, from 2014 to 2015. Using an ultrasound machine, 79 sets of prostatic measurements were recorded at a urinary bladder volume of 50–99 mL (V1 as our reference volume), and at least one of three other urinary bladder volumes (V2 = 100–199 mL, V3 = 200–299 mL and V4 = 300–399 mL), in 66 males. Twelve of the participants had multiple sets of prostate volume measurements. SPSS was used to analyse the data. T‐test, Bland‐Altman plots and linear regression were used to compare and test for the existence of proportional biases in measurements. Results There was a statistically significant difference in prostatic volumes recorded at V1 and V2 (P = 0.017). However, the prostatic volume differences recorded for V1/V3, and V1/V4 groups of data were all not statistically significant (P > 0.05). The limits of agreement for the set of measurements spread from approximately −29 to +18 mL for V1/V2, −48 to +36 mL for V1/V3 and −12 to +12 mL for V1/V4 variables. There was no proportional bias in the V1/V2 (P = 0.55) and V1/V4 (P = 0.463) measurements. Conclusion Urinary bladder volume of 50–99 mL produces prostatic volume measurements comparable to volumes measured in patients with a full (300–399 mL), or nearly full urinary bladder (200–299 mL). A urinary bladder volume of 50–99 mL may therefore be adequate for scanning the prostate gland, and is likely to be tolerated much better by patients.

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Actualités concernant la prise en charge non chirurgicale du cancer de la prostate localisé

Drouin¹,

Rouprêt²

2009

Progrès en Urologie

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Magnetic Resonance Imaging Prostate Volumes Could be Used as a Surrogate for Transrectal Ultrasound Volumes in Estimating Iodine-125 Seeds Required in Brachytherapy

Cited by 3 publications

References 2 publications

Variability in MRI vs. ultrasound measures of prostate volume and its impact on treatment recommendations for favorable-risk prostate cancer patients: a case series

Variability in MRI vs. ultrasound measures of prostate volume and its impact on treatment recommendations for favorable-risk prostate cancer patients: a case series

Prostatic volume determination by transabdominal ultrasonography: Does accuracy vary significantly with urinary bladder volumes between 50 to 400 mL?

Actualités concernant la prise en charge non chirurgicale du cancer de la prostate localisé

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