Abstract:Uterine cervix is the lower constricted part of uterus which is best evaluated by magnetic resonance imaging (MRI) due to its higher soft tissue and contrast resolution. The cervical cancer is a common gynecological cancer causing much morbidity and mortality especially in developing countries. Cervical carcinomas mainly occurs in reproductive age group with prognosis mainly depending on the extent of disease at the time of diagnosis, hence it is important to identify these cancerous lesions early and stage th… Show more
“…Magnetic resonance imaging (MRI) is highly sensitive to changes in soft tissues and is extensively used in the screening and diagnostic process of cervical cancer (9,10). Diffusion-weighted imaging (DWI) can display the diffusion movement of water molecules in living tissues to distinguish normal tissues from malignant cells and aid in clinical diagnosis (9,11). It has been widely employed because of this benefit, and the clinical application impact is positive (9,11).…”
Section: Introductionmentioning
confidence: 99%
“…Diffusion-weighted imaging (DWI) can display the diffusion movement of water molecules in living tissues to distinguish normal tissues from malignant cells and aid in clinical diagnosis (9,11). It has been widely employed because of this benefit, and the clinical application impact is positive (9,11). The apparent diffusion coefficient (ADC) obtained from DW images was also successfully introduced into the quantitative characteristics of cervical cancer (9,10).…”
Background Cervical cancer (CC) is the second most common cancer in women worldwide. Diffusion-weighted imaging (DWI) plays an important role in the diagnosis of CC, but the conventional techniques are affected by many factors. Purpose To compare reduced-field-of-view (r-FOV) and full-field-of-view (f-FOV) DWI in the diagnosis of CC. Material and Methods Preoperative magnetic resonance imaging (MRI) with r-FOV and f-FOV DWI images were collected. Two radiologists reviewed the images using a subjective 4-point scale for anatomical features, magnetic susceptibility artifacts, visual distortion, and overall diagnostic confidence for r-FOV and f-FOV DWI. The objective features included the region of interest (ROI) signal intensity of the cervical lesion (SIlesion) and gluteus maximus muscle (SIgluteus), standard deviation of the background noise (SDbackground), signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR). The differences of measured apparent diffusion coefficient (ADC) values between the two examinations in pathological grades and FIGO tumor stages were compared. Results A total of 200 patients were included (170 with squamous cell carcinoma and 30 with adenocarcinoma). The scores of anatomical features, magnetic susceptibility artifacts, visual distortion, and overall diagnostic confidence for r-FOV DWI were significantly higher than those for f-FOV DWI. There was no difference in SNR and CNR between r-FOV DWI and f-FOV DWI. There were significant differences in ADC values between the two groups in all comparisons ( P < 0.05). Conclusion Compared with f-FOV DWI, r-FOV DWI might provide clearer imaging, fewer artifacts, less distortion, and higher image quality for the diagnosis of CC and might assist in the detection of CC.
“…Magnetic resonance imaging (MRI) is highly sensitive to changes in soft tissues and is extensively used in the screening and diagnostic process of cervical cancer (9,10). Diffusion-weighted imaging (DWI) can display the diffusion movement of water molecules in living tissues to distinguish normal tissues from malignant cells and aid in clinical diagnosis (9,11). It has been widely employed because of this benefit, and the clinical application impact is positive (9,11).…”
Section: Introductionmentioning
confidence: 99%
“…Diffusion-weighted imaging (DWI) can display the diffusion movement of water molecules in living tissues to distinguish normal tissues from malignant cells and aid in clinical diagnosis (9,11). It has been widely employed because of this benefit, and the clinical application impact is positive (9,11). The apparent diffusion coefficient (ADC) obtained from DW images was also successfully introduced into the quantitative characteristics of cervical cancer (9,10).…”
Background Cervical cancer (CC) is the second most common cancer in women worldwide. Diffusion-weighted imaging (DWI) plays an important role in the diagnosis of CC, but the conventional techniques are affected by many factors. Purpose To compare reduced-field-of-view (r-FOV) and full-field-of-view (f-FOV) DWI in the diagnosis of CC. Material and Methods Preoperative magnetic resonance imaging (MRI) with r-FOV and f-FOV DWI images were collected. Two radiologists reviewed the images using a subjective 4-point scale for anatomical features, magnetic susceptibility artifacts, visual distortion, and overall diagnostic confidence for r-FOV and f-FOV DWI. The objective features included the region of interest (ROI) signal intensity of the cervical lesion (SIlesion) and gluteus maximus muscle (SIgluteus), standard deviation of the background noise (SDbackground), signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR). The differences of measured apparent diffusion coefficient (ADC) values between the two examinations in pathological grades and FIGO tumor stages were compared. Results A total of 200 patients were included (170 with squamous cell carcinoma and 30 with adenocarcinoma). The scores of anatomical features, magnetic susceptibility artifacts, visual distortion, and overall diagnostic confidence for r-FOV DWI were significantly higher than those for f-FOV DWI. There was no difference in SNR and CNR between r-FOV DWI and f-FOV DWI. There were significant differences in ADC values between the two groups in all comparisons ( P < 0.05). Conclusion Compared with f-FOV DWI, r-FOV DWI might provide clearer imaging, fewer artifacts, less distortion, and higher image quality for the diagnosis of CC and might assist in the detection of CC.
“…Magnetic resonance imaging (MRI), due to the higher resolution of soft tissues that characterizes it, is currently the best method for imaging the normal anatomy of the cervix and evaluating cervical lesions. Magnetic resonance imaging is estimated to be of significant help in the challenging differential diagnosis of cervical fibroids from adnexal tumors [ 16 ]. On MRI, cervical leiomyomas appear as a well-defined, rounded, T2 hypo-isointense lesion showing homogeneous enhancement centered on the cervix.…”
Large cervical leiomyomas (≥10cm) are extremely rare. Our case report concerns the surgical treatment of a patient with a large cervical leiomyoma associated with chronic pelvic pain, bilateral hydroureteronephrosis and significant impairment of renal function. A 47-year-old patient of reproductive age with a normal menstrual cycle and a medical history of chronic pelvic pain presented to the gynecology clinic for examination. Clinically, the presence of a large pelvic mass was found, the upper margins of which were palpable at the level of the umbilicus. A preoperative assessment revealed bilateral hydroureteronephrosis due to obstructive uropathy and renal dysfunction. Hydroureteronephrosis, as a consequence of the large pelvic mass, probably originating from the cervix of the uterus, was evaluated as the main cause of renal dysfunction. Tumor markers were negative. The imaging studies confirmed the clinical diagnosis of uterine leiomyoma, and the surgical treatment of the patient with laparotomy was decided. Intraoperatively, the presence of a large uterine cervical fibroid was detected, and a total abdominal hysterectomy and bilateral adnexectomy were performed. Operating was difficult, with significant surgical difficulties. The postoperative course was uneventful, without immediate complications. The patient's symptom relief began gradually, immediately after surgery. Three months after surgery, the patient reported complete relief of her pelvic pain. A re-examination of the urinary tract revealed complete recovery of renal morphology and function. In the paper, after the presentation of the case, a brief review of cervical leiomyomas is attempted based on the literature, mainly regarding the diagnostic and therapeutic approach.
“…We read with interest the pictorial essay, “Magnetic Resonance Imaging of Uterine Cervix: A Pictorial Essay,” by Gala et al 1 The article is an excellent depiction of various pathologies affecting uterine cervix. However, we would like to make the following contributions.…”
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