Magnetic Resonance Imaging of the Wrist: Diagnostic Performance Statistics

Hobby, J. L.; Tom, Brian D. M.; Bearcroft, P.W.P.; Dixon, Adrian K.

doi:10.1053/crad.2000.0571

Cited by 107 publications

(81 citation statements)

References 42 publications

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“…Berger 17 Devillé 18 Fiellin 19 * Gould 20 * Hobby 21 Hoffman 22 Hoogendam 23 * Huicho 24 Hurley 25 Kelly 26 Kim 27 * Kwok 28 Balk 15 and Lau 16 Lederle 29 Mitchell 30 * Mol 31 * Nelemans 32 Safriel 33 * Sloan 34 Sonnad 35 Vasquez 36 Visser 37 *…”

Section: Specificity Sensitivitymentioning

confidence: 99%

Variation of a test’s sensitivity and specificity with disease prevalence

Leeflang

Rutjes

Reitsma

et al. 2013

CMAJ

427

315

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Research CMAJBackground: Anecdotal evidence suggests that the sensitivity and specificity of a diagnostic test may vary with disease prevalence. Our objective was to investigate the associations between disease prevalence and test sensitivity and specificity using studies of diagnostic accuracy. Methods:We used data from 23 meta-analyses, each of which included 10-39 studies (416 total). The median prevalence per review ranged from 1% to 77%. We evaluated the effects of prevalence on sensitivity and specificity using a bivariate random-effects model for each metaanalysis, with prevalence as a covariate. We estimated the overall effect of prevalence by pooling the effects using the inverse variance method.Results: Within a given review, a change in prevalence from the lowest to highest value resulted in a corresponding change in sensitivity or specificity from 0 to 40 percentage points. This effect was statistically significant (p < 0.05) for either sensitivity or specificity in 8 metaanalyses (35%). Overall, specificity tended to be lower with higher disease prevalence; there was no such systematic effect for sensitivity. Interpretation:The sensitivity and specificity of a test often vary with disease prevalence; this effect is likely to be the result of mechanisms, such as patient spectrum, that affect prevalence, sensitivity and specificity. Because it may be difficult to identify such mechanisms, clinicians should use prevalence as a guide when selecting studies that most closely match their situation. Abstract

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Section: Specificity Sensitivitymentioning

confidence: 99%

Variation of a test’s sensitivity and specificity with disease prevalence

Leeflang

Rutjes

Reitsma

et al. 2013

CMAJ

427

315

View full text Add to dashboard Cite

show abstract

“…Contrary to MRI-related imaging studies of the wrist, the evidence of the diagnostic value of plain radiographic examinations is quite scarce, involving study populations of no more than 84 wrists in 59 normal patients or 102 wrists in symptomatic patients [9,11,21]. In our analysis we were able to prove the accuracy of the scapholunate angle, the radiolunate angle and the scapholunate gap as diagnostic tools.…”

Section: Discussionmentioning

confidence: 77%

The significance of conventional radiographic parameters in the diagnosis of scapholunate ligament lesions

et al. 2010

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“…[1][2][3][4][5] In particular, direct MR arthrography (D-MRA) of the wrist joint provides high tissue contrast and can be more sensitive and accurate than conventional MRI in delineating and evaluating the ligaments of the wrist. 1,6,7 Three-dimensional (3D) isotropic MRI at 3.0 T can provide multiplanar reformation along arbitrary planes that can be helpful in evaluating complex musculoskeletal structures.…”

Section: Introductionmentioning

confidence: 99%

Diagnostic performance of wrist magnetic resonance (MR) arthrography: comparison of three-dimensional isotropic T 1 weighted fast spin-echo MR arthrography and two-dimensional MR arthrography

Yoon

Park

2017

The British Journal of Radiology

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Objective: To compare the diagnostic performance of direct wrist MR arthrography (D-MRA) with twodimensional (2D) T 1 weighted fast spin-echo (FSE) and three-dimensional (3D) isotropic T 1 weighted FSE sequences for detecting triangular fibrocartilage (TFC) central perforations and scapholunate ligament (SLL) and lunotriquetral ligament (LTL) tears. Methods: 26 patients who had undergone pre-operative wrist D-MRA with 2D and 3D isotropic T 1 weighted FSE sequences and subsequent arthroscopic surgeries were included. Each MRI sequence was independently evaluated and scored by two readers retrospectively for the presence of TFC central perforations and SLL and LTL tears. Arthroscopic findings were used as the reference standard. Diagnostic performance was evaluated by using the area under the receiver operating characteristic curve. The sensitivity, specificity and accuracy of both sequences for diagnosing the injuries were calculated. Results: Arthroscopic surgery revealed 21 TFC central perforations, 7 SLL tears and 3 LTL tears. The area under the receiver operating characteristic curve value of 2D and 3D for central perforations in TFC and tears in SLL and LTL was identical or similar (0.667-0.947). The sensitivity, specificity and accuracy of both sequences for diagnosing the injury of each structure were not significantly different (TFC, 90.5/80/88.5% for both readers/sequences; SLL, 100/89.5/92.3% for both readers' 2D and Reader A's 3D, and 85.7/89.5/ 88.5% for Reader B's 3D; LTL, 66.7/100/96.2% for both readers' 2D and 33.3/100/92.3% for both readers' 3D). Interobserver agreements were substantial to excellent. Conclusion: In wrist D-MRA, the diagnostic performances of 3D isotropic and 2D T 1 weighted FSE sequences are comparable for TFC central perforations and SLL and LTL tears. Advances in knowledge: The diagnostic performance of 3D isotropic T 1 weighted FSE D-MRA and that of 2D T 1 weighted FSE D-MRA were not significantly different in the diagnosis of central perforations in the TFC and tears in the SLL and LTL. 3D isotropic T 1 weighted FSE D-MRA has potential for substituting 2D imaging.

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Magnetic Resonance Imaging of the Wrist: Diagnostic Performance Statistics

Cited by 107 publications

References 42 publications

Variation of a test’s sensitivity and specificity with disease prevalence

Variation of a test’s sensitivity and specificity with disease prevalence

The significance of conventional radiographic parameters in the diagnosis of scapholunate ligament lesions

Diagnostic performance of wrist magnetic resonance (MR) arthrography: comparison of three-dimensional isotropic T 1 weighted fast spin-echo MR arthrography and two-dimensional MR arthrography

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