Magnetic Resonance Imaging of Intramedullary Spinal Cord Lesions: A Pictorial Review

Do-Dai, Daniel D.; Brooks, Michael K.; Goldkamp, Allison L.; Erbay, Sami H.; Bhadelia, Rafeeque A.

doi:10.1067/j.cpradiol.2009.05.004

Cited by 74 publications

(87 citation statements)

References 16 publications

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“…Dermoid cysts are rare benign lesions within in the central nervous system and are usually located in the lumbosacral region [4,6]. Often combined with associated spinal dysraphism, their etiology is not completely understood.…”

Section: Discussionmentioning

confidence: 99%

“…Due to the widely accepted theory of embryological malformation during the closure of the neural groove with ectoderm getting trapped under the lines of fusion of the ectodermal folds, dermoid cysts are not considered to be true neoplasms [8,9]. An extramedullary location (60%) is more common than an intramedullary one (40%) [4]. Lumbo-sacral accumulation may develop from the last closing, caudal part of the neural tube, making this region the most likely to be affected by cutaneous tissue getting trapped within the developing tube, giving rise…”

Section: Discussionmentioning

confidence: 99%

“…All symptoms of a major space occupying lesion in the spinal cord can be seen, but vary in their intensity. A slight male predominance is described in the literature [3,4]. Although dermoid cysts are benign, two cases of malignant transformation have been described in the literature by Naoko in 2007.…”

mentioning

confidence: 99%

“…Arising from an embryologic miss-development during the ectodermal folds, dermoid cysts often present themselves in the 2nd or 3 rd decade [3]. The symptoms result from their space-occupying effect causing irritation or compression of adjacent neural structures [3,4]. Especially the rupture of a dermoid cyst can be associated with a high morbidity and mortality [5].…”

Section: Introductionmentioning

confidence: 99%

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Unruptured Spinal Dermoid Cyst with Progressive Paraplegia

Hj¹,

Henker²,

Erbersdobler³

et al. 2017

Med Case Rep

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Intramedullary dermoid cysts without spinal dysraphism are uncommon tumors. Only a few cases have been reported in the literature. We report a case of a 63-yearold woman with a spinal intramedullary dermoid cyst without rupture, but with progressive paraparesis and bladder dysfunction. Lumbar magnetic resonance imaging showed a large cystic lesion with inhomogeneous contrast enhancement and compression of the conus medullaris. Operation and histopathological examination confirmed a dermoid cyst. A follow up MRI imaging and examination was performed 4, 8 and 20 months after the operation. This case report adds to the few previous reported cases of intramedullary unruptured dermoid cysts and summarizes the latest literature.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Unruptured Spinal Dermoid Cyst with Progressive Paraplegia

Hj¹,

Henker²,

Erbersdobler³

et al. 2017

Med Case Rep

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“…These signal changes are considered to reflect various intramedullary lesions. 10,11 To date, post-operative MRI has not yet been fully studied in relation to the correlation of morphology or signal change of cervical cord and longer term prognosis in patients with SCIWORET. 5,[12][13][14] In our study, we have focused on quantitative analysis of signal intensity (SI) and transverse area (TA) of the spinal cord on T2-weighted MRI pre-and postoperatively.…”

Section: Introductionmentioning

confidence: 99%

Quantitative magnetic resonance imaging analysis correlates with surgical outcome of cervical spinal cord injury without radiologic evidence of trauma

Shen

2014

Spinal Cord

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Study design: Prospective study. Objectives: To investigate whether pre-and post-operative changes of signal intensity (SI) and transverse area (TA) of the spinal cord on T2-weighted magnetic resonance imaging (MRI) reflect the surgical outcome in patients with spinal cord injury (SCI) without radiologic evidence of trauma (SCIWORET). Setting: The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China. Methods: In 36 consecutive prospective patients, MRI was performed pre-operatively and 3 months post-operatively. The Japanese Orthopaedic Association (JOA) scale and the American Spinal Cord Injury Association (ASIA) motor score (AMS) were used to quantify neurologic status at admission and at least 12-month follow-up. Pre-and post-operative TA, range of signal intensity (RSI), grayscale of signal intensity (GSI) and prevertebral hyperintensities (PVHs) were measured using the image analysis software. Pre-operative status and post-operative recovery were assessed in relation to MRI parameters pre-and post-operatively using univariate and multivariate analysis. Results: Pre-operative JOA and AMS score negatively correlates RSI, GSI and PVH. There was no significant correlation between pre-operative TA and pre-operative JOA and AMS. Recovery rate with JOA negatively correlates pre-operative RSI, post-operative RSI, pre-operative GSI, post-operative GSI and PVH. There was a significant negative correlation between recovery rate with AMS and pre-operative RSI, post-operative GSI and PVH. From these results of multivariate stepwise regression analysis, the predictors of surgical outcomes are pre-operative GSI and pre-operative RSI. Conclusion: Quantitative MRI analysis may provide reliable information for the prediction of the initial neurological status and surgical outcome of patients with SCIWORET.

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