Magnetic Resonance Imaging of Gastric Motility in Conscious Rats
Xiaokai Wang,
Fatimah Alkaabi,
Ashley Cornett
et al.
Abstract:IntroductionGastrointestinal (GI) magnetic resonance imaging (MRI) can simultaneously capture gastric peristalsis, emptying, and intestinal filling and transit. Performing GI MRI with animals requires anesthesia, which complicates physiology and confounds interpretation and translation from animals to humans. This study aims to enable MRI in conscious rats, and for the first time, characterize GI motor functions in awake versus anesthetized conditions.MethodsWe acclimated rats to remain awake, still, and minim… Show more
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