Magnetic Resonance Imaging of Cutaneous Neoplasms: Clinicopathologic Correlation

Zemtsov, Alexander; Lorig, Ronald; Ng, Thian C.; Xue, Ming; Bailin, Philip L.; Bergfeld, Wilma F.; Larson, Karen; Yetman, Randall J.

doi:10.1111/j.1524-4725.1991.tb03976.x

Cited by 43 publications

(23 citation statements)

References 25 publications

(37 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Expressed in terms of voxel size, the resolution achieved is an order of magnitude higher than reported in prior work. At a voxel size on the order of 2 x lo-'' mm3 an SNR of [5][6][7][8][9][10] in the dermis and Gradient-echo ROI signal versus echo time in the dorsal calf (156 x 936 x 1,500 pm3 voxel size; smallest dimension perpendicular to the skin surface). The solid line for the dermis was obtained by fitting the data to a sum of two exponentials (T2* = 9.8 ms, 91 % and 42.7 ms, 9%).…”

Section: Discussionmentioning

confidence: 99%

In vivo MR microscopy of the human skin

Song

Wehrli

1997

Magnetic Resonance in Med

View full text Add to dashboard Cite

The requirements for imaging the skin are dictated by the organ's layered structure, which extends only a few millimeters from the surface and thus demands extremely high resolution in this direction. While less critical, resolution in the remaining two dimensions determines whether the skin's accessory structures can be resolved. The problem is compounded by short transverse relaxation times, in particular of the dermis, the structure of most clinical interest. In this work images of the normal human skin were obtained in vivo at voxel sizes as small as 19 x 78 x 800 microm3, by means of customized 3D gradient and partial flip-angle spin-echo pulse sequences and very small transmit/receive coils on a 1.5T clinical imager equipped with high-power whole-body gradients. Structures resolved include hair follicles and the sublayers of the dermis. The very short time constant for the major component (91%) for transverse relaxation in the dermis (T2* approximately 10 ms) suggests the potential of substantial gains in achievable signal-to-noise ratio by shortening the echo time.

show abstract

Section: Discussionmentioning

confidence: 99%

In vivo MR microscopy of the human skin

Song

Wehrli

1997

Magnetic Resonance in Med

View full text Add to dashboard Cite

show abstract

“…The first cross-sec tional images of the skin in vivo obtained by MR imaging were presented by our reserarch team in Liège during the Symposium on Bioengineering and the Skin in 1986 [13]. Since this date, different research teams have written about in vivo MR imaging of normal [14][15][16] and pathologic skin [17,18]. MR imaging is also available for characterizing the skin by the measurement of relaxation times in the different skin layers as it may give information about the physicochemical prop erties of the skin in vivo [19].…”

Section: Introductionmentioning

confidence: 99%

In vivo Hydration Profile in Skin Layers by High-Resolution Magnetic Resonance Imaging

Querleux

Richard

Bittoun

et al. 1994

Skin Pharmacol Physiol

View full text Add to dashboard Cite

In recent years magnetic resonance imaging has become a very efficient tool for in vivo quantification of water content and water behavior in living tissues. We have applied this technique to the study of the in vivo hydration profile in heel skin layers by quantification of the mobile water proton density versus depth. Effects of a bath, a moisturizer and repeated soaping are present. Hydration profiles by magnetic resonance imaging delineate two different structures in stratum corneum: an outer layer where hydration can be modified by external mechanisms and an inner layer where hydration is not altered. The main interest of this method lies in the fact that the physical signal is exactly located, as spatial encoding is the basis of in vivo imaging. This method differs from other noninvasive methods which acquire an averaged signal from a nondelimited volume of interest.

show abstract

“…ZEMTSOV et al (21) reported that, according to good clinico-pathological correlations observed in 5 patients, MR imaging may be useful in melanotic skin lesions. Although their spatial resolution was not as good as that used in the present study, the authors obtained clinically helpful images of squamous cell carcinomas, dermatofibromas, and primary cutaneous B-cell lymphomas.…”

Section: Discussionmentioning

confidence: 99%