Magnetic Resonance Imaging (MRI) Compatible Ultrasound Therapeutic System

Abstract

We present a portable instrument for a comprehensive particle and particle motion analysis for a large variety of applications. The instrument presently exists as a prototype. It combines two optical techniques which were originally developed for astrophysically-motivated laboratory research. One is based on bright-field microscopy to image micrometre-sized particles and to give structural information. The other is based on stroboscopic trajectory imaging to yield the motion of particles. The latter is applicable for particle sizes down to less than 100 nm. The direction of a particle and its speed can be determined. Due to a long focal distance (80 mm), the instrument does not interfere with the particles and their environment but can be used for in situ and real-time measurements.

Effect of Echo-Guided High-Intensity Focused Ultrasound Ablation on Localized Experimental Tumors

“…It is difficult to examine the region to be ablated by conventional ultrasonography. Magnetic resonance imaging (MRI) is also useful in demonstrating the extent of damaged tissue [1]. T2-weighted images show regions of tissue necrosis clearly.…”

“…MRI is a useful technique for following the progress of tissue destruction in vivo following ultrasound exposure. It has also been shown that tissue volumes in which the temperature is elevated can be visualized using MRI [1]. HIFU in combination with an MRI system may be used in the future in veterinary medicine.…”

Staircase-Voltage Metal–Oxide–Semiconductor Field-Effect Transistor Driver Circuit for Therapeutic Ultrasound

“…High intensity focused ultrasound (HIFU) is attracting interest as a new modality for treating a tumor. [1][2][3][4] A HIFU system needs to transmit a higher time-average ultrasonic power than an ultrasound imaging system, and a common practice is to use a piezoelectric transducer to generate ultrasound waves. An important component of the system is high-voltage drivers to excite such a transducer, which typically consists of a number of array elements.…”

Comparison of Sound Pressure Distribution Determined by Numerical Analysis and Scaled-Up Experiment for Small Ultrasonic Probe with Lens

“…Ultrasonic medical equipment is used in not only diagnosis but also therapy such as that for treating hyperthermia. Highintensity focused ultrasound (HIFU) 1) is a typical application using high-power ultrasound. Many researchers are also studying high-frequency ultrasonic imaging systems with interluminal or catheter transducers.…”