Abstract:Since chest X-ray and CT scan features of Kaposi's sarcoma (KS) are nonspecific, we wanted to test the hypothesis that the histological components of this tumour and/or the associated haemorrhagic component, may result in a characteristic signal pattern on magnetic resonance imaging (MRI). Thoracic MRI was performed in a prospective manner in ten patients with acquired immune deficiency syndrome (AIDS) and pulmonary KS. MRI examinations (1.5 Tesla) included Spin-echo T1 (SE-T1), before and after gadolinium inj… Show more
“…16 Magnetic resonance imaging features of AIDS-related KS include reduced signal intensity on T2weighted images, hyperintense areas on T1-weighted images, and strong tumor enhancement after gadopentetate dimeglumine injection. 17…”
A woman in her 30s presented with recurrent low-grade fever and cough (onset, 1 week). She reported occasional night sweats and weight loss of approximately 20 pounds over the past 4 months. She denied nausea, vomiting, diarrhea, or any urinary complaints. Her past medical history was significant for chronic hepatitis C and HIV infection, the latter diagnosed in 2001. She was noncompliant with highly active antiretroviral therapy for more than 4 years and had pneumocystis pneumonia 2 years prior to this presentation. She had a 10-pack per year smoking history and reported active use of cocaine and heroin. The patient denied any occupational exposures.
“…16 Magnetic resonance imaging features of AIDS-related KS include reduced signal intensity on T2weighted images, hyperintense areas on T1-weighted images, and strong tumor enhancement after gadopentetate dimeglumine injection. 17…”
A woman in her 30s presented with recurrent low-grade fever and cough (onset, 1 week). She reported occasional night sweats and weight loss of approximately 20 pounds over the past 4 months. She denied nausea, vomiting, diarrhea, or any urinary complaints. Her past medical history was significant for chronic hepatitis C and HIV infection, the latter diagnosed in 2001. She was noncompliant with highly active antiretroviral therapy for more than 4 years and had pneumocystis pneumonia 2 years prior to this presentation. She had a 10-pack per year smoking history and reported active use of cocaine and heroin. The patient denied any occupational exposures.
“…In one study of patients with established pulmonary KS, characteristic findings of MRI included an increased signal intensity on T1-weighted images, markedly reduced signal intensity on T2-weighted images, and strong lesional contrast enhancement after administration of gadolinium. 110 This pattern of signal abnormalities, particularly when seen in a peribronchial vascular distribution, was most suggestive of KS. Further analyses will better define how specific this finding is for pulmonary KS and what role MRI may have in evaluating pulmonary disease in patients with HIV infection.…”
“…So far, a variety of sequence types has been evaluated for lung nodule detection with MRI. The spectrum comprises T2-weighted fast spin echo imaging with and without fat saturation [23–26], inversion recovery techniques [27], T1-spin echo [26, 28] and gradient echo sequences [29, 30]. Fig.…”
Section: Experience With Mri For the Evaluation Of Pathological Condimentioning
BackgroundAmong the modalities for lung imaging, proton magnetic resonance imaging (MRI) has been the latest to be introduced into clinical practice. Its value to replace X-ray and computed tomography (CT) when radiation exposure or iodinated contrast material is contra-indicated is well acknowledged: i.e. for paediatric patients and pregnant women or for scientific use. One of the reasons why MRI of the lung is still rarely used, except in a few centres, is the lack of consistent protocols customised to clinical needs.MethodsThis article makes non-vendor-specific protocol suggestions for general use with state-of-the-art MRI scanners, based on the available literature and a consensus discussion within a panel of experts experienced in lung MRI.ResultsVarious sequences have been successfully tested within scientific or clinical environments. MRI of the lung with appropriate combinations of these sequences comprises morphological and functional imaging aspects in a single examination. It serves in difficult clinical problems encountered in daily routine, such as assessment of the mediastinum and chest wall, and even might challenge molecular imaging techniques in the near future.ConclusionThis article helps new users to implement appropriate protocols on their own MRI platforms.Main Messages• MRI of the lung can be readily performed on state-of-the-art 1.5-T MRI scanners.• Protocol suggestions based on the available literature facilitate its use for routine• MRI offers solutions for complicated thoracic masses with atelectasis and chest wall invasion.• MRI is an option for paediatrics and science when CT is contra-indicated
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
