Magnetic resonance imaging features of intra-articular tenosynovial giant cell tumor in children

Nguyen, Jie C.; Biko, David M.; Nguyen, Michael K.; Othman, Sammy; Weber, Kristy; Ganley, Theodore J.; Arkader, Alexandre

doi:10.1007/s00247-020-04861-4

Cited by 5 publications

(12 citation statements)

References 30 publications

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“…TSGCTs. In a previous study, diffuse subtypes were more common than localized subtypes [5]. There is no clear de nition to distinguish between diffuse and localized TSGCTs.…”

Section: Discussionmentioning

confidence: 88%

“…Diffuse TSGCTs were characterized by lesions with multiple synovial-like structures or pathological villous structures. TSGCTs have been reported to have low to intermediate signal intensity on both T1-and T2weighted MR images [4][5][6]. In this study, additional ndings of cystic changes on T2 weighted imaging were investigated.…”

Section: Methodsmentioning

confidence: 99%

“…TSGCTs are reported to have low to intermediate signal intensity on both T1-and T2-weighted MR images. This rather low signal intensity is thought to be due to the presence of hemosiderin deposition [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

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T2-star (T2*) -weighted magnetic resonance imaging of tenosynovial giant cell tumors

Sakamoto

Noguchi

Matsuda

2022

Preprint

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Objective Tenosynovial giant cell tumors (TSGCTs) are benign but aggressive lesions. Low to intermediate signal intensity on both T1- and T2-weighted images on magnetic resonance imaging (MRI) is characteristic, possibly reflecting hemosiderin deposition. T2-star (T2*)-weighted MR images reflect the paramagnetic deoxyhemoglobin, methemoglobin, or hemosiderin in the lesions and surrounding tissues. Materials and methods In 23 TSGCT patients (6 male and 17 females), the T2* MRI findings, the cystic changes confirmed on the T2-weighted image, potentially characteristic of TSGCT, were analyzed.Results The tumor locations included 10 large joints including nine knees and one ankle, 10 small joints including six fingers and four toes, and three wrists/hands. Ten diffuse and 13 localized tumors were predominantly located in the large joints and small joints, respectively. Cystic changes were seen in five (22%), predominantly in the large joints. The T2*-weighted images indicated three signal patterns of low, iso and high signal intensity compared to muscle. The low-, iso- and high-signal intensities were seen in 22 (96%), 23 (100%) and 12 (52%) of the locations, respectively. To distinguish TSGCTs from the surrounding tissue, the low intensity T2*-weighted images and low to intermediate intensity T1-weighted images when compared to muscle and fluid, respectively were useful for the large joints. Low to intermediate intensity on T1- or T2-weighted images was useful to distinguish TSGCTs from subcutaneous tissue in the small joints.Discussion MRI using T2*-, as well as T1 and T2-weighted images, is useful to assess the extent of TSGCTs within tissue, which is important for surgical planning.Institutional Review Board ApprovalThis report has been approved by the institutional review board of our institution (R2499).

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“…TSGCTs. In a previous study, diffuse subtypes were more common than localized subtypes [5]. There is no clear de nition to distinguish between diffuse and localized TSGCTs.…”

Section: Discussionmentioning

confidence: 88%

Section: Methodsmentioning

confidence: 99%

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T2-star (T2*) -weighted magnetic resonance imaging of tenosynovial giant cell tumors

Sakamoto

Noguchi

Matsuda

2022

Preprint

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Section: Raspravaunclassified

“…Zbog svoje specifičnosti i osjetljivosti MR je danas zlatni standard u dijagnostici LTGCT-a, a koristi se i za poslijeoperacijsko praćenje (18). Na MR snimci LTGCT se karakteristično prikazuje kao heterogena nodularna masa niskog signala na T1 i T2 mjerenoj slici te se može precizno utvrditi njegova veličina i položaj (18). Hemosiderin koji se nakuplja u proliferiranoj sinovijalnoj ovojnici posjeduje paramagnetska svojstva te se na T1 i T2 mjerenoj snimci prikazuju točkaste nakupine hemosiderina unutar lezije (18).…”

Section: Raspravaunclassified

Localized tenosynovial gigantocellular tumor of the ankle in an adolescent: case report and literature review

Dimnjaković¹,

Karakaš²,

Bojanić³

2022

Paediatr Croat

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Tenosynovial giant cell tumor (TGCT) is a rare, benign monoarticular disease that affects the synovial lining of joint, tendon or bursa. We distinguish two forms of the disease, localized and diffuse forms, both of which are histologically identical. The incidence rate of the localized form of TGCT (LTGCT) is 10 cases per million people, of which about 5% of all cases occur in the ankle. We present a rare case of LTGCT in the anterior part of the ankle in an adolescent, which was manifested by swelling and occasional pain, especially during sports activities. On the magnetic resonance imaging (MRI) a heterogeneously structured, well encapsulated tumor was visible in the anterior part of the ankle. In addition to the painless swelling in the anterior part of the ankle, the physical examination revealed a deficit of dorsiflexion of the foot. The operation was performed arthroscopically but the tumor could not be removed in a single piece due to its size, so it was removed in multiple pieces. Histopathological analysis confirmed that the tumor was TGCT. During the two-year follow-up period, the patient did not have problems with the operated ankle and no recurrence of the disease was observed on control MRIs. TGCT should be considered as a possible differential diagnosis, especially when pain and swelling of the ankle occur without injury. Arthroscopic surgery is a safe and effective method of treatment if it is performed by an experienced surgeon backed by a welltrained team. The choice of the type of surgical treatment should be determined depending on the anatomical position of the formation in the joint and the surgeon’s assessment and preference.

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T2-star (T2*)-weighted magnetic resonance imaging of tenosynovial giant cell tumors

Sakamoto

Noguchi

Matsuda

2023

European Journal of Radiology Open

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Magnetic resonance imaging features of intra-articular tenosynovial giant cell tumor in children

Cited by 5 publications

References 30 publications

T2-star (T2*) -weighted magnetic resonance imaging of tenosynovial giant cell tumors

T2-star (T2*) -weighted magnetic resonance imaging of tenosynovial giant cell tumors

Localized tenosynovial gigantocellular tumor of the ankle in an adolescent: case report and literature review

T2-star (T2*)-weighted magnetic resonance imaging of tenosynovial giant cell tumors

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