Magnetic resonance imaging, clinical manifestations, and management of Rathke's cleft cyst

Nishioka, Hiroshi; Haraoka, Jo; Izawa, Hitoshi; Ikeda, Yukio

doi:10.1111/j.1365-2265.2006.02446.x

Cited by 125 publications

(189 citation statements)

References 16 publications

Supporting

Mentioning

173

Contrasting

Unclassified

Order By: Relevance

“…Notably, an acute presentation mimicking pituitary apoplexy was found in three of our patients; similar cases have been infrequently described (14,17,18). Headache was the most common clinical feature at presentation (67%), in accord with previously reported studies (55-81%) (4,11,13,14,16,(19)(20)(21)(22)(23). It has been proposed that the presence of headaches does not correlate with the cyst size and it is more common in patients with high and iso-intense cyst content on T1-weighted MR images, with mucous cyst content and with intense chronic inflammation of the cyst wall (21).…”

Section: Discussionsupporting

confidence: 80%

“…the cyst size and is observed only in cysts with high and iso-intensity on T1-weighted MR images (20). Notably, syndrome of inappropriate secretion of ADH has also been rarely reported (4,20,22). In five of our cases, the RCC co-existed with a pituitary adenoma.…”

Section: Discussionmentioning

confidence: 85%

“…Major visual field defects were identified in 58% of the subjects. In previous studies, the frequency ranges between 38 and 49% (4,5,12,14,16,20,22) with the size of the cyst correlating with the presence of visual deterioration (20). At presentation, the reported rates of pituitary hormone deficits show wide variation (17-81%) also depending on the method of assessment (5,11,12,14,16,19,20,22,23).…”

Section: Discussionmentioning

confidence: 99%

“…It has been proposed that anterior hypopituitarism is not related to Figure 1 Recurrence-free probability following surgical management of RCC (nZ32). the cyst size and is observed only in cysts with high and iso-intensity on T1-weighted MR images (20). Notably, syndrome of inappropriate secretion of ADH has also been rarely reported (4,20,22).…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Outcome in surgically treated Rathke's cleft cysts: long-term monitoring needed

Trifănescu¹,

Stavrinides²,

Plaha³

et al. 2011

European Journal of Endocrinology

View full text Add to dashboard Cite

Objective: To clarify the outcome of all cases of Rathke's cleft cysts (RCC) treated surgically and followed up in Oxford during a long-term period. Subjects and methods: The records of all patients with RCC seen in the Department of Endocrinology between January 1978 and June 2009 were reviewed. Results: A total of 33 patients (20 females, median age 43 years) were identified. At presentation, major visual field defects were detected in 58% of patients and gonadotrophin, ACTH and TSH deficiency in 60, 36 and 36% of patients respectively. Desmopressin treatment was required in 18% of patients. Treatment consisted of cyst evacuation combined with or without biopsy/removal of the wall. Post-operatively, visual fields improved in 83% of patients with impairment, whereas there was no reversal of ACTH or TSH deficiency or of diabetes insipidus. All but one subject had imaging follow-up during a mean period of 48 months (range 2-267). Cyst relapse was detected in 22% of patients at a mean interval of 29 months (range 3-48 months); in 57% of them, the recurrence was symptomatic. Relapse-free rates were 88% at 24-months and 52% at 48-months follow-up. At last assessment, at least quadrantanopia was reported in 19% of patients, gonadotrophin, ACTH and TSH deficiency in 50, 42 and 47% of patients respectively. Desmopressin treatment was required in 39% of patients. Conclusions: In this study of patients with RCC and long-term follow-up, we showed a considerable relapse rate necessitating long-term monitoring. Surgical intervention is of major importance for the restoration of visual field defects, but it does not improve endocrine morbidity, which in the long-term affects a substantial number of patients.

show abstract

Section: Discussionsupporting

confidence: 80%

Section: Discussionmentioning

confidence: 85%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Outcome in surgically treated Rathke's cleft cysts: long-term monitoring needed

Trifănescu¹,

Stavrinides²,

Plaha³

et al. 2011

European Journal of Endocrinology

View full text Add to dashboard Cite

show abstract

“…On MRI RCC usually does not exhibit destruction or enlargement of the sella turcica 4 , but there is in our case. Intracystic nodules, that are waxy nodules, if present, show characteristically intensity on MRI 5 . RCCs are almost always homogeneous in MR intensity, except for waxy nodules, whereas other lesions such as cystic craniopharyngioma and hemorrhagic adenomas are less frequently homogeneous 6 .…”

Section: Discussionmentioning

confidence: 99%

Rathke's cleft cyst and partial feet adactyly: an unusual association

Gondim

Schops

Cavalcante

et al. 2007

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

-A 53 year-old woman presented a recurrent bifrontal headache of 2 years duration and bilateral progressive visual disturbance. The clinical and neurological examination showed a bilateral feet adactyly and bitemporal hemianopsia. The brain MRI demonstrated a Rathke´s cleft cyst. The patient was operated by a transnasal endoscopic approach. It seems that this unusual association has never been described before.KEY WORDS: adactyly, endoscopic, pituitary surgery, pituitary tumor, rathke´s cleft cyst, transnasal approach.Cisto de Rathke e adactilia parcial dos pés: uma associação rara RESUMO -Mulher de 53 anos com história recorrente de cefaléia com duração de 2 anos bilateral e progressiva, acompanhada de distúrbios visuais. O exame clinico e neurológico mostrou uma adactilia dos pés e hemianopsia bitemporal. A ressonância nuclear magnética cerebral mostrou um cisto de Rathke. A paciente foi operada por via transnasal endoscópica. Aparentemente esta é a primeira vez que esta associação é descrita na literatura.PALAVRAS-CHAVE: adactilia, endoscopia, cirurgia hipofisária, cisto de rathke, tumor de hipófise, via transnasal.

show abstract

Houssay phenomenon: a rare case of diabetes remission

Zhang

2011

Practical Diabetes

View full text Add to dashboard Cite

Magnetic resonance imaging, clinical manifestations, and management of Rathke's cleft cyst

Cited by 125 publications

References 16 publications

Outcome in surgically treated Rathke's cleft cysts: long-term monitoring needed

Outcome in surgically treated Rathke's cleft cysts: long-term monitoring needed

Rathke's cleft cyst and partial feet adactyly: an unusual association

Houssay phenomenon: a rare case of diabetes remission

Contact Info

Product

Resources

About