Magnetic Particle Imaging: Visualization of Instruments for Cardiovascular Intervention

Abstract

http://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.12120424/-/DC1.

A comprehensive literatures update of clinical researches of superparamagnetic resonance iron oxide nanoparticles for magnetic resonance imaging

“…One key characteristic and fundamental difference of MPI compared with other imaging modalities is the high magnetic moment (about 108 times higher than protons) and the fast relaxivity (about 104 times faster than protons in water) of SPIOs (148,149). In the framework of the Magnetic Particle Imaging Technology consortium, funded by the German Federal Ministry of Education and Research, the University of Lübeck and Philips Technology Innovative Technologies (Hamburg, Germany) created a cooperation initiative to develop this technique (150). MPI depicts the spatial distribution of SPIO particles by using oscillating magnetic fields.…”

“…Haegele et al (151,152) reported an approach to visualize a commercially available diagnostic catheter and guide wire for use in MPI guided vascular interventions using a very thin Resovistcoating and a dedicated MPI system. Haegele et al (150) reported that by using MPI, both balloon catheters could be visualized with high temporal resolution and sufficient spatial resolution (Figure 20). Kakite et al (153) evaluated the usefulness of administration of Resovist and MRI for assessing the efficacy of radiofrequency liver ablation.…”

Magnetic particle imaging: kinetics of the intravascular signal in vivo

“…Possible application scenarios for MPI might include cardiovascular imaging and even guidance of cardiovascular interventions. 3,4 In principle, MPI would allow visualization and quantification of vascular pathologies while also being able to determine additional functional parameters in one examination. Further, MPI could be used as an imaging method for percutaneous transluminal coronary angioplasty, if indicated.…”

On the way to a patient table integrated scanner system in magnetic particle imaging

“…4, 6, 15 The idea of integrating a single-sided MPI scanner 16 into a patient table to enable an exact navigation of instruments by the received three-dimensional information is a very promising approach for medical interventions. 17,18 Especially in the proposed interventional scenarios in a catheter laboratory a good patient access and a large FOV are required.…”