Magnetic Particle Imaging: Artifact-Free Metallic Stent Lumen Imaging in a Phantom Study

Wegner, Franz; Friedrich, Thomas; Gladiss, Anselm von; Grzyska, Ulrike; Sieren, M; Lüdtke‐Buzug, Kerstin; Frydrychowicz, Alex; Buzug, Thorsten M.; Barkhausen, Jörg; Haegele, Julian

doi:10.1007/s00270-019-02347-x

Cited by 13 publications

(10 citation statements)

References 27 publications

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“…This is confirmed by the visual comparison of the MPI images and the almost identical correlation coefficients (stented phantoms/reference phantoms vs nominal diameter). A recently published multimodality study proposed MPI to overcome material induced artifacts of coronary stents in MRI and CT. 16 Our study proves the potential of artifact free stent lumen imaging with MPI, based on the signal characteristics of stents with a wide range of different diameters and materials. Although stents do not generate MPI signal and therefore do not cause material induced artifacts, a number of general artifacts requires discussion.…”

Section: Discussionsupporting

confidence: 58%

“…In these cases, only invasive imaging with x-ray-based digital subtraction angiography (DSA) offers both, the possibility to diagnose and treat the stent occlusion free of material-induced artifacts. However, first pilot results suggest MPI may overcome this disadvantage by allowing noninvasive artifact free stent lumen visualization in comparison with MRI and CT. 16 MPI's spatial resolution (<1 mm) is comparable to CT and MRI. 17 The acquisition time (per frame) is in the range of milliseconds and thus MPI is much faster than the established modalities.…”

Section: Introductionmentioning

confidence: 97%

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Magnetic Particle Imaging: In vitro Signal Analysis and Lumen Quantification of 21 Endovascular Stents

Wegner¹,

Gladiss²,

Haegele³

et al. 2021

IJN

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Section: Discussionsupporting

confidence: 58%

Section: Introductionmentioning

confidence: 97%

Magnetic Particle Imaging: In vitro Signal Analysis and Lumen Quantification of 21 Endovascular Stents

Wegner¹,

Gladiss²,

Haegele³

et al. 2021

IJN

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“…In contrast to CT and MRI, the stent lumen can be assessed without artifacts in MPI [ 8 ]. Recently, Herz et al demonstrated the potential of MPI to guide percutaneous transluminal angioplasties of vascular stenoses [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

Heating of an Aortic Stent for Coarctation Treatment During Magnetic Particle Imaging and Magnetic Resonance Imaging—A Comparative In Vitro Study

Grzyska

Friedrich

Sieren

et al. 2021

Cardiovasc Intervent Radiol

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Purpose To evaluate heating of a redilatable stent for the treatment of aortic coarctation in neonates and small children in the new imaging modality magnetic particle imaging and established magnetic resonance imaging. Materials and Methods The cobalt-chromium stent (BabyStent, OSYPKA AG, Rheinfelden, Germany) has a stent design which allows for redilatation and adjustment of the diameter from 6 to 16 mm for a use in aortic coarctation. The stent loses its radial integrity while opening at predetermined breaking points at a diameter of 14 mm or 16 mm, respectively. We measured the temperature increase in the stent at different diameters during 7-min magnetic particle imaging and magnetic resonance imaging scans with fiber optic thermometers under static conditions surrounded by air. In magnetic particle imaging, stents with diameters from 6 to 16 mm were tested while in magnetic resonance imaging only stents with diameters of 6 mm and 14 mm were investigated exemplarily. Result In magnetic particle imaging, the measured temperature differences increased up to 4.7 K with growing diameters, whereas the opened stents with discontinuous struts at 14 and 16 mm showed only minimal heating of max. 0.5 K. In contrast to magnetic particle imaging, our measurements showed no heating of the stents during magnetic resonance imaging under identical conditions. Conclusion The BabyStent did show only slight heating in magnetic particle imaging and no detectable temperature increase in magnetic resonance imaging.

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“…To detect signal loss caused by the iron of the Bayoxide E8706 particles, we used gadolinium-based contrast agent to reduce T1 of the surrounding medium for improved signal void delineation, in combination with T1-weighted imaging. According to already published measurement protocols, Gadovist (Bayer, Berlin, Germany) in a dilution of 1:200 was chosen [ 23 , 24 ]. The phantom was aligned longitudinally within the scanner.…”

Section: Methodsmentioning

confidence: 99%

Bimodal Interventional Instrument Markers for Magnetic Particle Imaging and Magnetic Resonance Imaging—A Proof-of-Concept Study

Wegner

Lüdtke‐Buzug

Cremers³

et al. 2022

Nanomaterials

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The purpose of this work was to develop instrument markers that are visible in both magnetic particle imaging (MPI) and magnetic resonance imaging (MRI). The instrument markers were based on two different magnetic nanoparticle types (synthesized in-house KLB and commercial Bayoxide E8706). Coatings containing one of both particle types were fabricated and measured with a magnetic particle spectrometer (MPS) to estimate their MPI performance. Coatings based on both particle types were then applied on a segment of a nonmetallic guidewire. Imaging experiments were conducted using a commercial, preclinical MPI scanner and a preclinical 1 tesla MRI system. MPI image reconstruction was performed based on system matrices measured with dried KLB and Bayoxide E8706 coatings. The bimodal markers were clearly visible in both methods. They caused circular signal voids in MRI and areas of high signal intensity in MPI. Both the signal voids as well as the areas of high signal intensity were larger than the real marker size. Images that were reconstructed with a Bayoxide E8706 system matrix did not show sufficient MPI signal. Instrument markers with bimodal visibility are essential for the perspective of monitoring cardiovascular interventions with MPI/MRI hybrid systems.

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Magnetic Particle Imaging: Artifact-Free Metallic Stent Lumen Imaging in a Phantom Study

Cited by 13 publications

References 27 publications

Magnetic Particle Imaging: In vitro Signal Analysis and Lumen Quantification of 21 Endovascular Stents

Magnetic Particle Imaging: In vitro Signal Analysis and Lumen Quantification of 21 Endovascular Stents

Heating of an Aortic Stent for Coarctation Treatment During Magnetic Particle Imaging and Magnetic Resonance Imaging—A Comparative In Vitro Study

Bimodal Interventional Instrument Markers for Magnetic Particle Imaging and Magnetic Resonance Imaging—A Proof-of-Concept Study

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