Magnetic Nanoparticles: High‐Throughput, Protein‐Targeted Biomolecular Detection Using Frequency‐Domain Faraday Rotation Spectroscopy (Small 12/2017)

Abstract

In article number 1602862, Shawn A. Putnam and co‐workers, revisiting a 170 year old magneto‐optical phenomenon, reveal a fast, sensitive, and versatile medical test. Polarized light interacts with functionalized magnetic nanoparticles in the biomolecule characterization method called fd‐FRS (frequency‐domain Faraday Rotation Spectroscopy). Alternating magnetic fields induce particle rotation and realignment with the magnetic field – a process dependent on the size, conformation, and density of the conjugated biomolecules.