Magnetic nanoparticles coated with polysaccharide polymers for potential biomedical applications

Covaliu, Cristina Ileana; Berger, Daniela; Matei, Cristian; Diamandescu, L.; Vasile, Eugeniu; Cristea, Camelia; Ioniţă, Valentin; Iovu, Horia

doi:10.1007/s11051-011-0452-6

Cited by 55 publications

(25 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this study, we synthesized nanoparticles using co-precipitation method [1,2,13-15,37,38], dispersed them in monomeric methyl methacrylate with styrene (MMAS), and polymerized this composition using pre-polymerization method.…”

Section: Methodsmentioning

confidence: 99%

“…Pronounced superparamagnetic [1-4] and ferromagnetic [5] properties at room temperature enable the use of these nanoparticles in magnetic resonance imaging [6-9] and biosensing [9] as well as in drug delivery and drug uptake applications [8-13]. Because they possess magneto-optical properties [14,15], Fe 3 O 4 nanoparticles have also been used to develop tunable filters [16,17] and optical switches [18,19] that operate under magnetic fields.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Photo-induced electric polarizability of Fe3O4 nanoparticles in weak optical fields

et al. 2013

View full text Add to dashboard Cite

Using a developed co-precipitation method, we synthesized spherical Fe3O4 nanoparticles with a wide nonlinear absorption band of visible radiation. Optical properties of the synthesized nanoparticles dispersed in an optically transparent copolymer of methyl methacrylate with styrene were studied by optical spectroscopy and z-scan techniques. We found that the electric polarizability of Fe3O4 nanoparticles is altered by low-intensity visible radiation (I ≤ 0.2 kW/cm2; λ = 442 and 561 nm) and reaches a value of 107 Å3. The change in polarizability is induced by the intraband phototransition of charge carriers. This optical effect may be employed to improve the drug uptake properties of Fe3O4 nanoparticles.PACS33.15.Kr78.67.Bf42.70.Nq

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Photo-induced electric polarizability of Fe3O4 nanoparticles in weak optical fields

et al. 2013

View full text Add to dashboard Cite

show abstract

“…Mucoadhesivity of the The magnetic nanoparticles have tendency to agglomerate due to strong magnetic dipole-dipole attractions between particles. Therefore, one of the main problems in producing stable magnetic particles is to prevent the agglomeration during the synthesis and coating process [7]. Different types of water-soluble polymers like polyethylene glycol (PEG), dextran, chitosan, and starch are used to prevent the agglomeration and to enhance the biocompatibility of iron oxide nanoparticles [8].…”

Section: Introductionmentioning

confidence: 99%

Carboxymethyl starch-coated iron oxide magnetic nanoparticles: a potential drug delivery system for isoniazid

et al. 2015

View full text Add to dashboard Cite

show abstract

“…26 Luo and co-workers synthesized and characterized Fe 3 O 4 /PPy/P (MAA-co-AAm) tri-layered composite microspheres as a pH responsive device. [30][31][32][33][34][35] Although, a number of studies have been reported on multilayered composites based on conductive polymers, [5][6][7]25,[35][36][37] there is still no report which is focused on multilayered nanocomposites of conductive polymers, Fe 3 O 4 and polyxanthone. 28 Antar and co-workers synthesized carbon nanotube/graphite/poly(lactic acid) conductive biopolymer nanocomposites (CPC) by a melt process and investigated their thermoelectric behavior.…”

Section: Introductionmentioning

confidence: 99%

Innovative magnetic tri-layered nanocomposites based on polyxanthone triazole, polypyrrole and iron oxide: synthesis, characterization and investigation of the biological activities

et al. 2015

View full text Add to dashboard Cite

A magnetic multi-functional composite with a tri-layer core-shell-shell construction was successfully prepared by a combination process involving click reactions and emulsion polymerization. Firstly, magnetic polyxanthone triazole (PXT) was synthesized via the click reaction of bisethynyl and 2,7-(N-2chloroacetamide) xanthone (NClX) in the presence of Fe 3 O 4 nanoparticles. Then, a polypyrrole@polyxanthone triazole@Fe 3 O 4 (PPy@PXT@Fe 3 O 4 ) tri-layered nanocomposite was prepared via emulsion polymerization of pyrrole in the presence of magnetic PXT using sodium dodecyl sulfate (SDS) as an emulsifier and ammonium persulfate (APS) as an oxidant. Characterization of the synthesized polymer and nanocomposite was carried out by nuclear magnetic resonance (NMR), Fourier transform infrared (FT-IR), X-ray diffraction (XRD), scanning electron microscopy (SEM), thermal gravimetric analysis (TGA), Brunauer-Emmett-Teller (BET) survey, transmission electron microscopy (TEM) and vibrating sample magnetometer (VSM) studies. Also, the antioxidant activity of the nanocomposites was examinedand compared with the bare polymer using a 2,2-diphenyl-1-picryl-hydrazyl free radical (DPPHc) assay.In addition, the in vitro antibacterial activities of the di-layered and tri-layered nanocomposites were studied by inhibition zone methods. The results showed a greater synergic effect in the thermal stability, antioxidant and antibacterial activities of the tri-layered nanocomposite than of the di-layered nanocomposite. Thus, the developed PPy@PXT@Fe 3 O 4 tri-layered nanocomposite could be used effectively for biomedical applications and would be a good sorbent candidate for the microbial treatment of wastewater.

show abstract

Magnetic nanoparticles coated with polysaccharide polymers for potential biomedical applications

Cited by 55 publications

References 16 publications

Photo-induced electric polarizability of Fe3O4 nanoparticles in weak optical fields

Photo-induced electric polarizability of Fe3O4 nanoparticles in weak optical fields

Carboxymethyl starch-coated iron oxide magnetic nanoparticles: a potential drug delivery system for isoniazid

Innovative magnetic tri-layered nanocomposites based on polyxanthone triazole, polypyrrole and iron oxide: synthesis, characterization and investigation of the biological activities

Contact Info

Product

Resources

About