Magnetic nanoparticle clusters for photothermal therapy with near-infrared irradiation

Nanoscale Clustering and Magnetic Properties of Mn x Fe3−x O4 Particles Prepared from Natural Magnetite

“…Therefore, this increases the saturation magnetization (12.85 %) due to the effect of the increasing Mn doping and particle sizes of the clusters. Recently, Shen et al reported that the magnetite nanoparticles in bigger clusters have a higher saturation magnetization than smaller clusters and individual particles [2], which is in accordance with this experiment. Further, for x = 0.5, 0.75, and 1, the theoretical calculation of the saturation magnetization increased by approximately 12.5, 18.75, and 25 %, respectively.…”

“…Magnetic nanomaterials are highly desirable due to the enormous possibilities they offer in a broad range of applications in biomedical applications [1], photothermal therapy [2], as radiosensitizers in cancer therapy [3], in hydrophobic drug delivery [4], as supercapacitors [5], in copper removal from water [6], as adsorbents of toxic heavy metals [7], and many others. Among the magnetic nanomaterials, magnetite (Fe 3 O 4 ) nanoparticles are the most extensively studied because they can be manipulated and controlled with an external magnetic field.…”

“…However, they did not investigate whether there was a magnetic saturation effect originating from the clustering of the particles. To study the magnetic properties of the Mn x Fe 3−x O 4 nanoparticles in more detail, we examined their saturation magnetization dependence not only on the Mn content but also on the presence of the primary particles (or individual particles as defined by [2,17]) and the secondary structures. The secondary structures are defined as the clusters of the primary particles.…”

Polydopamine-Coated Magnetic Composite Particles with an Enhanced Photothermal Effect

“…The photothermal effect that how strong a PTC agent can convert optical energy into heat depends on both PTC efficiency and the absorbance intensity in the NIR region. 22 Although 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 18 subdivided into groups of with and without NIR laser exposure. The cytotoxic results were shown in Figure 5a.…”

Hyaluronan-modified superparamagnetic iron oxide nanoparticles for bimodal breast cancer imaging and photothermal therapy

“…9,[12][13][14][15] Chen et al 14 reported that the highly crystallized iron oxide nanoparticles administered through the tail vein for PTT as effective and biodegradable mediators. These injected nanoparticles are likely to be applied for PTT as a result of the enhanced permeability and retention (EPR) effect and is cleared from the body through urinary excretion without long-term toxicity.…”