Magnetic molecular imprinted polymers for in vitro controlled release and solid-phase extraction of dextromethorphan: synthesize, characterization, and application

Surface molecularly imprinted polymers based on magnetic multi‐walled carbon nanotubes for the highly selective purification of resveratrol from crude extracts of Vitis vinifera, Arachis hypogaea, and Polygonum cuspidatum

“…Molecularly imprinted polymers (MIPs) can specifically recognize target molecules via binding sites and have been widely used in biomedical, biosensor, environmental, and food analysis fields [7][8][9]. However, conventional MIPs require complex post-processing including crushing, grinding, and sieving, and suffer from problems such as deeply buried pores, slow mass transfer, and difficult elution [10].…”

Synthesis and Properties of Cefixime Core–Shell Magnetic Nano-Molecularly Imprinted Materials

“…MMIPs can not only specifically adsorb target molecules in a complex environment, but they can also be quickly separated by an external magnetic field, thus avoiding steps such as centrifugation, resulting in low cost, mild conditions, reducing material waste, and improving work efficiency [29,30]. Fatemeh Mirzapour et al prepared the MMIPs of dextromethorphan via precipitation polymerization using Fe 3 O 4 @SiO 2 -C=C as the carrier and applied them to highly selective solid phase extraction; the recovery was 92-97%, and the adsorption capacity was 114.8 mg/g [31]. Chaoren Yan et al used Fe 3 O 4 @SiO 2 as the carrier and developed a combination of epigallocatechin-3-gallate (EGCG), imprinting technology, and magnetic nanoparticles to obtain a somewhat promising nanomaterial (MINs@EGCG) for amyloid inhibition, drug carrier, and facile separation triple functions; the cleansing efficiency was up to 80% [32].…”

“…In this work, the sol-gel method was introduced to imprint molecules into the inorganic network structures to form a rigid structure. Compared with precipitation polymerization, radical polymerization, and other methods, this method is simple in operation, easy to control, and low cost [31,[37][38][39]. Fe 3 O 4 @SiO 2 was the core, and MIPs were used as the shell; silica was used as the intermediate carrier to connect the magnetic particles and the organic layer.…”