Magnetic Heating of Fe–Co Ferrites — Experiments and Modeling

Kekalo, Katsiaryna; Shubitidze, Fridon; Meyers, Robert; Yaqub, Rumana; Baker, I.

doi:10.1142/s1793984416500070

Cited by 2 publications

(2 citation statements)

References 14 publications

(16 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several studies have reported that the heating response of CoFe alloy nanoparticles to a variable magnetic field could be determined by regulating the proportion of cobalt. 48 , 49 Compared to magnetite (Fe 3 O 4 ) and cobalt ferrite (CoFe 2 O 4 ) MNPs, CoFe NPs with an adjustable thermal response exhibit high-efficiency therapeutic potential and specific loss power (SLP) in tumors. 49 , 50 …”

Section: Classification Of Mnpsmentioning

confidence: 99%

See 1 more Smart Citation

Advances in Brain Tumor Therapy Based on the Magnetic Nanoparticles

Xu,

Zhang,

Zhang

et al. 2023

IJN

View full text Add to dashboard Cite

Brain tumors, including primary gliomas and brain metastases, are one of the deadliest tumors because effective macromolecular antitumor drugs cannot easily penetrate the blood-brain barrier (BBB) and blood-brain tumor barrier (BTB). Magnetic nanoparticles (MNPs) are considered the most suitable nanocarriers for the delivery of brain tumor drugs because of their unique properties compared to other nanoparticles. Numerous preclinical and clinical studies have demonstrated the potential of these nanoparticles in magnetic targeting, nuclear magnetic resonance, magnetic thermal therapy, and ultrasonic hyperthermia. To further develop and optimize MNPs for the diagnosis and treatment of brain tumors, we attempt to outline recent advances in the use of MNPs to deliver drugs, with a particular focus on their efficacy in the delivery of anti-brain tumor drugs based on magnetic targeting and low-intensity focused ultrasound, magnetic resonance imaging for surgical real-time guidance, and magnetothermal and ultrasonic hyperthermia therapy. Furthermore, we summarize recent findings on the clinical application of MNPs and the research limitations that need to be addressed in clinical translation.

show abstract

Section: Classification Of Mnpsmentioning

confidence: 99%

“… 48 , 49 Compared to magnetite (Fe 3 O 4 ) and cobalt ferrite (CoFe 2 O 4 ) MNPs, CoFe NPs with an adjustable thermal response exhibit high-efficiency therapeutic potential and specific loss power (SLP) in tumors. 49 , 50 …”

Section: Classification Of Mnpsmentioning

confidence: 99%

Advances in Brain Tumor Therapy Based on the Magnetic Nanoparticles

Xu,

Zhang,

Zhang

et al. 2023

IJN

View full text Add to dashboard Cite

show abstract

Cobalt magnetic nanoparticles as theranostics: Conceivable or forgettable?

Petrarca

Poma

Vecchiotti

et al. 2020

Nanotechnology Reviews

View full text Add to dashboard Cite

Superparamagnetic nanoparticles, exposed to an external variable magnetic field, undergo rapid excitation/relaxation. So-called soft magnets, typically iron-based, rapidly and completely relax when the magnetic field returns to zero. Instead, cobalt-based (CoB) hard magnets retain residual magnetization, a characteristic related with the procedure for nanoparticles (NPs) production. Many researchers are still attracted by the potential of CoB NPs for theranostics as multifaced signal probes for imaging, microrobots, enhanced thermo/radiation therapy, and drug release. Since iron oxide NPs are the only magnetic NPs approved for human use, they are of reference for analyzing the potential of the disregarded CoB NPs. In vitro observed toxicity of CoB NPs, largely attributable to cobalt ions and other chemical species released by dissolution, excluded them from further investigations in humans. Nevertheless, experimental evidences documenting the in vivo toxicity of engineered CoB NPs remain very few. The surface functionalization adds newer properties and could improve the biocompatibility of NPs, critical for the clinical exploitation. In our opinion, it would be worth to further exploit the potential of finely tunable properties of CoB NPs in in vivo systems in order to establish a systematic database of properties and effects suitable for human application.

show abstract

Magnetic Heating of Fe–Co Ferrites — Experiments and Modeling

Cited by 2 publications

References 14 publications

Advances in Brain Tumor Therapy Based on the Magnetic Nanoparticles

Advances in Brain Tumor Therapy Based on the Magnetic Nanoparticles

Cobalt magnetic nanoparticles as theranostics: Conceivable or forgettable?

Contact Info

Product

Resources

About