a b s t r a c tBiocompatible hybrid particles composed of hydroxyapatite (Ca 10 (PO 4 ) 6 (OH) 2 , HAp) and ferrite (g-Fe 2 O 3 and Fe 3 O 4 ) were synthesized using a two-step procedure. First, the ferrite particles were synthesized by co-precipitation. Second, the suspension, which was composed of ferrite particles by a co-precipitation method, Ca(NO 3 ) 2 , and H 3 PO 4 aqueous solution with surfactant, was nebulized into mist ultrasonically. Then the mist was pyrolyzed at 1000 1C to synthesize HAp-ferrite hybrid particles. The molar ratio of Fe ion and HAp was (Fe 2 + and Fe 3 + )/HAp ¼6. The synthesized hybrid particle was round and dimpled, and the average diameter of a secondary particle was 740 nm. The cross section of the synthesized hybrid particles revealed two phases: HAp and ferrite. The ferrite was coated with HAp. The synthesized hybrid particles show a saturation magnetization of 11.8 emu/g. The net saturation magnetization of the ferrite component was calculated as 32.5 emu/g. The temperature increase in the AC-magnetic field (370 kHz, 1.77 kA/m) was 9 1C with 3.4 g (the ferrite component was 1.0 g). These results show that synthesized hybrid particles are biocompatible and might be useful for magnetic transport and hyperthermia studies.