Magnetic fields to align natural and synthetic fibers

Smal, Noor; Löwik, Dennis W. P. M.

doi:10.1016/b978-0-08-102015-9.00017-4

Cited by 4 publications

(1 citation statement)

References 59 publications

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“…It was shown that engineering the texture of the tissues can successively improve nerve growth or cause cancer cell proliferation and migration to cease [173]. Traditionally, the fibrils of collagen-based tissues were oriented by applying a large magnetic field because the collagen is diamagnetic and it reorients perpendicular to the applied field direction [174]. Due to the requirement of very large magnetic field, in order of several thousand Oersted, this method is limited to a very small volume of the tissue.…”

Section: Tissue Engineeringmentioning

confidence: 99%

A Guideline for Effectively Synthesizing and Characterizing Magnetic Nanoparticles for Advancing Nanobiotechnology: A Review

Kouhpanji

Stadler

2020

Sensors

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The remarkable multimodal functionalities of magnetic nanoparticles, conferred by their size and morphology, are very important in resolving challenges slowing the progression of nanobiotechnology. The rapid and revolutionary expansion of magnetic nanoparticles in nanobiotechnology, especially in nanomedicine and therapeutics, demands an overview of the current state of the art for synthesizing and characterizing magnetic nanoparticles. In this review, we explain the synthesis routes for tailoring the size, morphology, composition, and magnetic properties of the magnetic nanoparticles. The pros and cons of the most popularly used characterization techniques for determining the aforementioned parameters, with particular focus on nanomedicine and biosensing applications, are discussed. Moreover, we provide numerous biomedical applications and highlight their challenges and requirements that must be met using the magnetic nanoparticles to achieve the most effective outcomes. Finally, we conclude this review by providing an insight towards resolving the persisting challenges and the future directions. This review should be an excellent source of information for beginners in this field who are looking for a groundbreaking start but they have been overwhelmed by the volume of literature.

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Section: Tissue Engineeringmentioning

confidence: 99%

A Guideline for Effectively Synthesizing and Characterizing Magnetic Nanoparticles for Advancing Nanobiotechnology: A Review

Kouhpanji

Stadler

2020

Sensors

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Hierarchical Peptide‐ and Protein‐Based Biomaterials: From Molecular Structure to Directed Self‐assembly and Applications

Yuan¹,

Shi²,

Azevedo³

2022

Multifunctional Hydrogels for Biomedical Applications

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Magnetic Field-Induced Alignment of Nanofibrous Supramolecular Membranes: A Molecular Design Approach to Create Tissue-like Biomaterials

Radvar

Shi

Grasso

et al. 2020

ACS Appl. Mater. Interfaces

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A molecular design approach to fabricate nanofibrous membranes by self-assembly of aromatic cationic peptides with hyaluronic acid (HA) and nanofiber alignment under a magnetic field is reported. Peptides are designed to contain a block composed of four phenylalanine residues at the C-terminus, to drive their self-assembly by hydrophobic association and aromatic stacking, and a positively charged domain of lysine residues for electrostatic interaction with HA. These two blocks are connected by a linker with a variable number of amino acids and ability to adopt distinct conformations. Zeta potential measurements and circular dichroism confirm their positive charge and variable conformation (random coil, -sheet or -helix), which depend on the pH and sequence. Their self-assembly, examined by fluorescence spectroscopy, small-angle X-ray scattering and transmission electron microscopy, show the formation of fiber-like nanostructures in the micromolar range. When the peptides are combined with HA, hydrogels or flat membranes are formed. The molecular structure tunes the mechanical behavior of the membranes and the nanofibers align in the direction of magnetic field due to the high diamagnetic anisotropy of phenylalanine residues. Mesenchymal stem cells cultured on magnetically-aligned membranes elongate in direction of the nanofibers supporting their application for soft tissue engineering.

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Magnetic fields to align natural and synthetic fibers

Cited by 4 publications

References 59 publications

A Guideline for Effectively Synthesizing and Characterizing Magnetic Nanoparticles for Advancing Nanobiotechnology: A Review

A Guideline for Effectively Synthesizing and Characterizing Magnetic Nanoparticles for Advancing Nanobiotechnology: A Review

Hierarchical Peptide‐ and Protein‐Based Biomaterials: From Molecular Structure to Directed Self‐assembly and Applications

Magnetic Field-Induced Alignment of Nanofibrous Supramolecular Membranes: A Molecular Design Approach to Create Tissue-like Biomaterials

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