One of the few ways of obtaining neural information in humans is with evoked responses. Research in auditory evoked responses has gone through an evolution over the past 30 years. Initially, there was intense interest in the development of long latency responses (i.e. evoked responses with latencies exceeding 50 ms) as a method for 'objectively' assessing auditory system sensitivity. With the advent of more efficient computers, attention was focused on shorter latency responses beginning with the 'fast' responses (now referred to as middle latency responses) and then with the auditory brainstem response. The discovery of the auditory brainstem response brought forth an explosion of investigations that demonstrated the usefulness of this response for assessment of auditory system sensitivity and the transmission capabilities of the pontine auditory pathways. The bulk of these investigations occurred between 1975 and 1985. Beginning in the early 1980s and continuing today there has been renewed interest in both the middle and long latency auditory evoked responses and the nonmodality-specific endogenous responses. Interest in these electrical events with longer latencies is rooted in the knowledge that they originate from more rostral structures (midbrain, thalamus, cortex), and thus, provide us with information about auditory processing at a higher level than can be assessed with the auditory brainstem response. That is, these longer 1 Portions of this chapter were modified from references 34, 137, 244 and 245.