Magnetic Fe3O4@Au composite-enhanced surface plasmon resonance for ultrasensitive detection of magnetic nanoparticle-enriched α-fetoprotein

Liang, Ru‐Ping; Yao, Gui-Hong; Fan, Lijun; Qiu, Jian‐Ding

doi:10.1016/j.aca.2012.05.043

Cited by 132 publications

(54 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It was the evidence of the absorbance intensity of the Fe 3 O 4 NPs decreased monotonically with increasing light wavelength in the range of 300-800 nm(Fig. 1D, green curve), which is in agreement with results found in the literature[23,39]. When AuNPs were deposited onto the surface of Fe 3 O 4 NPs, an absorption peak at 526 nm was distinctly observed(Fig.…”

supporting

confidence: 89%

“…More recently, magnetic nanoparticles (MNPs) have received increasing attention in virtue of their high surface-to-volume ratios -that enables a high density of chemical to bind-and their excellent magnetic properties, which allow the direct capture and easy separation and concentration of targets in complex samples in an external magnetic field [23]. As a form of bifunctional material, magnetic Au nanoparticles-coated Fe 3 O 4 (AuNPs@Fe 3 O 4 ) combines the unique optical, electrical, and chemical properties of Au nanoparticles (AuNPs) and the paramagnetic property of magnetic nanoparticles at room temperature [24,25].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A novel electrochemical sensor based on magneto Au nanoparticles/carbon paste electrode for voltammetric determination of acetaminophen in real samples

Haghshenas

Madrakian

Afkhami

2015

Materials Science and Engineering: C

View full text Add to dashboard Cite

supporting

confidence: 89%

Section: Introductionmentioning

confidence: 99%

A novel electrochemical sensor based on magneto Au nanoparticles/carbon paste electrode for voltammetric determination of acetaminophen in real samples

Haghshenas

Madrakian

Afkhami

2015

Materials Science and Engineering: C

View full text Add to dashboard Cite

“…The use of nanomaterials in signal enhancement for the detection of an analyte in SPR has been intensely studied. Most commonly applied nanomaterials include latex nanoparticles [38], metallic nanoparticles e.g., gold and silver nanoparticles [39,40], magnetic nanoparticles [41,42], carbon-based nanostructures e.g., graphene [40,43] and liposome nanoparticles [41,44]. However, the use of the above nanoparticles in the enhancement of SPR-based assays of biological materials are predominantly for protein and small molecules.…”

Section: Sandwich Assay With Signal Amplification Using Aunpsmentioning

confidence: 99%

“…In most cases, the bacterium multiplies in chicken and the animal become a reservoir of the pathogen [7]. Campylobacter especially C. jejuni colonizes well in chicken since the microaerophilic conditions of chicken's intestine and its body temperature (41)(42) • C) are the optimum conditions for…”

Section: Introductionmentioning

confidence: 99%

Surface Plasmon Resonance Immunosensor for the Detection of Campylobacter jejuni

2017

View full text Add to dashboard Cite

Abstract:Campylobacteriosis is an internationally important foodborne disease caused by Campylobacter jejuni. The bacterium is prevalent in chicken meat and it is estimated that as much as 90% of chicken meat on the market may be contaminated with the bacterium. The current gold standard for the detection of C. jejuni is the culturing method, which takes at least 48 h to confirm the presence of the bacterium. Hence, the aim of this work was to investigate the development of a Surface Plasmon Resonance (SPR) sensor platform for C. jejuni detection. Bacterial strains were cultivated in-house and used in the development of the sensor. SPR sensor chips were first functionalized with polyclonal antibodies raised against C. jejuni using covalent attachment. The gold chips were then applied for the direct detection of C. jejuni. The assay conditions were then optimized and the sensor used for C. jejuni detection, achieving a detection limit of 8 × 10 6 CFU·mL −1 . The sensitivity of the assay was further enhanced to 4 × 10 4 CFU·mL −1 through the deployment of a sandwich assay format using the same polyclonal antibody. The LOD obtained in the sandwich assay was higher than that achieved using commercial enzyme-linked immunosorbent assay (ELISA) (10 6 -10 7 CFU·mL −1 ). This indicate that the SPR-based sandwich sensor method has an excellent potential to replace ELISA tests for C. jejuni detection. Specificity studies performed with Gram-positive and Gram-negative bacteria, demonstrated the high specific of the sensor for C. jejuni.

show abstract

“…14 Moreover, multichannel SPR biosensors make them possible to monitor biomolecular interactions and to quantify multiple biomarkers in a simultaneous manner. Nanomaterials, such as gold nanoparticles, 15 magnetic nanoparticles 16 and carbon nanotubes, 17 offer unique opportunities for creating highly sensitive and innovative performance of the SPR biosensors. Recently, graphene oxide (GO) has been reported to be a single-atom-thick, two-dimensional carbon material, which contains abundant oxygen functional groups, large surface areas, rich conjugation structure.…”

Section: Introductionmentioning

confidence: 99%

Graphene Oxide-Assisted Surface Plasmon Resonance Biosensor for Simple and Rapid Determination of D-Dimer in Plasma

Wang¹,

Lu²,

Zhang³

et al. 2016

j nanosci nanotechnol

View full text Add to dashboard Cite

In this article, a surface plasmon resonance (SPR) biosensor based on graphene oxide (GO) for simple and rapid determination of D-dimer in plasma is introduced. GO was conjugated onto the surface of the SPR chip surface via electrostatic interaction after the chip surface was activated with cysteamine. Subsequently, anti-D-dimer was covalently immobilized on the chip surface through binding between carboxylic groups on the GO surface and amine groups on the protein surface. Finally, label-free and rapid detection of D-dimer was carried out by the SPR biosensor via protein-protein interaction. After optimization, the concentration of GO was found to be 2 mg mL −1 . Meanwhile, this biosensor presented a response to D-dimer in the concentration range of 10-150 ng · mL −1 , and limit of detection (LOD) of the developed biosensor was determined to be as low as 5.08 ng · mL −1 .In addition, addition of albumin from human serum (HSA) to the anti-D-dimer-modified SPR chip revealed a negligible response, indicating a satisfactory immunological specificity. Furthermore, D-dimer detection was successfully conducted in different concentrations of human plasma. These results suggest that the GO-assisted SPR biosensor could be exploited for point-of-care diagnosis in the clinical laboratory in the future.

show abstract

Magnetic Fe3O4@Au composite-enhanced surface plasmon resonance for ultrasensitive detection of magnetic nanoparticle-enriched α-fetoprotein

Cited by 132 publications

References 49 publications

A novel electrochemical sensor based on magneto Au nanoparticles/carbon paste electrode for voltammetric determination of acetaminophen in real samples

A novel electrochemical sensor based on magneto Au nanoparticles/carbon paste electrode for voltammetric determination of acetaminophen in real samples

Surface Plasmon Resonance Immunosensor for the Detection of Campylobacter jejuni

Graphene Oxide-Assisted Surface Plasmon Resonance Biosensor for Simple and Rapid Determination of D-Dimer in Plasma

Contact Info

Product

Resources

About