Magnetic compression anastomosis for reconstruction of digestive tract after total gastrectomy in beagle model

Abstract

Obstructive jaundice (OJ) is a common problem in daily clinical practice. However, completely understanding the pathophysiological changes in OJ remains a challenge for planning current and future management. The effects of OJ are widespread, affecting the biliary tree, hepatic cells, liver function, and causing systemic complications. The lack of bile in the intestine, destruction of the intestinal mucosal barrier, and increased absorption of endotoxins can lead to endotoxemia, production of proinflammatory cytokines, and induce systemic inflammatory response syndrome, ultimately leading to multiple organ dysfunction syndrome. Proper management of OJ includes adequate water supply and electrolyte replacement, nutritional support, preventive antibiotics, pain relief, and itching relief. The surgical treatment of OJ depends on the cause, location, and severity of the obstruction. Biliary drainage, surgery, and endoscopic intervention are potential treatment options depending on the patient's condition. In addition to modern medical treatments, Traditional Chinese medicine may offer therapeutic benefits for OJ. A comprehensive search was conducted on PubMed for relevant articles published up to August 1970. This review discusses in detail the pathophysiological changes associated with OJ and presents effective strategies for managing the condition.

Enhanced hemocompatibility and rapid magnetic anastomosis of electrospun small-diameter artificial vascular grafts

“…First, magnetic anastomosis seals with magnetic fields instead of sutures, resulting in a more effective closure and eliminating leakage risk, as shown in prior intestinal( Chen et al, 2020 ; Zhang. et al, 2023a ), biliary( Jang et al, 2011 ), vascular( Yang et al, 2018 ; Zhang et al, 2023b ), and biliary-enteric ( Li et al, 2008b ) anastomoses. Second, magnetic anastomosis leaves no intraluminal sutures and creates a smoother anastomotic stoma, reducing turbulence and platelet adhesion.…”

Treatment of anastomotic stricture after rectal cancer operation by magnetic compression technique: A case report

“…Later, this technique was used in coronary artery bypass surgery[ 7 - 9 ]. With further development, MCT has been used in digestive tract anastomosis[ 10 - 12 ], therapeutic fistula[ 13 - 15 ], and ureteral stenosis anastomosis[ 16 , 17 ]. The combination of MCT and endoscopic technology has greatly expanded its application for the treatment of digestive tract lesions[ 18 , 19 ].…”