Magnesiummangel und Magnesiumtherapie bei Herzrhythmusstörungen

Vierling, W.; Liebscher, D.-H.; Micke, Oliver; Ehrlich, Bodo von; Kisters, Klaus

doi:10.1055/s-0033-1343206

Cited by 14 publications

(11 citation statements)

References 1 publication

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“…Many basic studies have shown that magnesium deficiency might be involved in the development of essential hypertension or borderline hypertension [14][15][16][17][18][19][20][21][22][23][24][25][37][38][39][40][41].…”

Section: Discussionmentioning

confidence: 99%

“…This Table 3 shows drugs that can trigger QT-prolongation and Torsade-de-pointes tachycardia, whereby a magnesium deficiency may worsen it [41]. Table 4 shows contraindications and side effects of magnesium therapy.…”

Section: Discussionmentioning

confidence: 99%

“…The MACH study could show the beneficial use of magnesium orotate as adjuvant therapy in patients on optimal treatment for severe congestive heart failure in a follow-up study of 1 year [35]. It is also well known, that magnesium has a significant value in the treatment of cardiac arrhythmia, Torsade-de-pointes tachycardia responds especially well to the intravenous administration of magnesium sulfate [26,41,[44][45][46][47][48][49][50]. There is however scant data for the treatment of heart failure with an additional magnesium therapy.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Positive Effect of Magnesium Orotate Therapy in Hypertensive Heart Disease

Kisters¹,

Gremmler²,

Schmidt³

et al. 2017

Metabolomics

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Positive Effect of Magnesium Orotate Therapy in Hypertensive Heart Disease

Kisters¹,

Gremmler²,

Schmidt³

et al. 2017

Metabolomics

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“…American Medical Association recommendations for prevention of cardiovascular disease includes established targets of Mg intake to be met on a daily basis [11]. Magnesium intake either as a supplement to meet RDA requirements or as a preventive agent in oral form is generally considered quite safe without any major potential for toxicity [12].…”

Section: Nutrition and Bioavailabilitymentioning

confidence: 99%

“…In light of Khan et al and Del Gobbo et al studies it is quite evident that hypomagnesemia should be corrected by oral magnesium supplementation to prevent cardiac rhythm disorders. According to recommendations made by German Society of Magnesium Research, supplementation of Mg can be used as a modality with or without other agents in management and prevention of rhythm disorders [12].…”

Section: Arrhythmiasmentioning

confidence: 99%

Dietary Magnesium Intake and Heart Health

Carpenter¹,

Zehra²,

Fatmi³

2018

Calcified Constrictive Pericarditis Treated With Ultrasonic Devices

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With magnesium being the second most common intracellular cation in the human body and the presence of hypomagnesemia in 10% of hospital admissions, magnesium deficiency has become a clinically significant nutritional deficiency in context of heart health. Magnesium has long been used as a treatment modality for cardiac arrhythmias as serum magnesium concentration of 1.44 mEq/L to 1.8 mEq/L has been found to have a statistically significant inverse association with cardiovascular disease events. Patients with the highest intake of magnesium were found to have incidents of sudden cardiac death reduced by 77% while hypomagnesemia is found to be associated with increased risk of congestive heart failure and cardiac arrhythmias. It has also been demonstrated that high dietary intake of serum magnesium is associated with decrease in systolic and diastolic blood pressure secondary to reduction in vascular tone and an increase in vasodilatory substances, like Prostaglandin E. Association of cardiovascular diseases with hypomagnesemia and the need for the fulfilment of RDA goals, authenticates the use of oral magnesium supplements, with established safety profile and lack of potential for toxicity.

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Hochdosiertes Magnesiumsulfat bei Aconitumintoxikation

et al. 2015

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This article reports the case of a 62-year-old male patient who ingested the roots of Monkshood (Aconitum napellus) and white hellebore (Veratrum album) dissolved in alcohol with a suicidal intention and suffered cardiotoxic and neurotoxic symptoms. After contacting the Poison Information Centre ventricular arrhythmia was treated with high-dose magnesium sulphate as the only antiarrhythmic agent and subsequently a stable sinus rhythm could be established after approximately 3 h. Aconitum napellus is considered the most poisonous plant in Europe and it is found in gardens, the Alps and the Highlands. Poisoning is mainly caused by the alkaloid aconite that leads to persistent opening and activation of voltage-dependent sodium channels resulting in severe cardiac and neurological toxicity. As no specific antidote is known so far, poisoning is associated with a high mortality. The therapy with high-dose magnesium sulphate is based on in vitro and animal experiments as well as limited clinical case reports.

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Magnesiummangel und Magnesiumtherapie bei Herzrhythmusstörungen

Cited by 14 publications

References 1 publication

Positive Effect of Magnesium Orotate Therapy in Hypertensive Heart Disease

Positive Effect of Magnesium Orotate Therapy in Hypertensive Heart Disease

Dietary Magnesium Intake and Heart Health

Hochdosiertes Magnesiumsulfat bei Aconitumintoxikation

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