Magnesium Malabsorption

Paunier, L

doi:10.1007/978-3-642-67239-2_2

Cited by 3 publications

(2 citation statements)

References 60 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…I f magnesium depletion continues, the bone store contributes by exchanging part of its content with extracellular fluid. Magnesium deficiency may result from reduced dietary intake of the ion, malabsorption (Paunier, 1979) and increased renal magnesium wasting (Abbott et al, 1994). Alcohol is now known as the most notorious cause of magnesium and riboflavin wasting.…”

Section: Introductionmentioning

confidence: 99%

Changes in Some Serum and Heamatological Indices in Magnesium and Riboflavin Deficiency in Rats

Adaikpoh¹,

Onyeneke²,

Eriyamremu³

et al. 2004

Pakistan J. of Nutrition

View full text Add to dashboard Cite

Levels of some serum metabolites were studied in wistar strain rats raised on diets deficient in magnesium (mg) and/or riboflavin (Rb). Though growth was suppressed in the rats fed the vitamin deficient (+Mg-Rb) and magnesium deficient (-Mg +Rb) diets, it was more retarded in those fed the double deficient diets (-Mg-Rb) when compared with the control (P<0.01; +Mg+Rb). Significant decreased levels were observed in the total protein and albumin of the Mg and Rb deficient groups when compared with the control (P<0.01). Only the double deficient group showed a significant reduction (P<0.01) in globulin levels. Creatinine and urea levels in all the groups were reduced when compared with the control while glucose and cholesterol levels were significantly increased (P<0.01) except in the (+Mg-Rb) group where a significant decrease (P<0.01) in glucose concentration was observed. The hemoglobin (Hb) concentration of the riboflavin deficient group showed a decrease of 19.2% when compared with the control. On the other hand, no marked differences were observed in the erythrocyte levels of the control and deficient groups. These results indicate that magnesium has similar effect as riboflavin deficiency on growth and the selected serum metabolites and that the severity increases with a deficiency of both micronutrients.

show abstract

Section: Introductionmentioning

confidence: 99%

Changes in Some Serum and Heamatological Indices in Magnesium and Riboflavin Deficiency in Rats

Adaikpoh¹,

Onyeneke²,

Eriyamremu³

et al. 2004

Pakistan J. of Nutrition

View full text Add to dashboard Cite

show abstract

“…Given intramuscularly, this solution may be both irritating and sclerosing; small amounts of lidocaine can be added to reduce discomfort [20]. It has been suggested that since sulfate ions bind calcium, mag nesium chloride might be preferred to magnesium sul fate for treating patients with coexisting hypocalcemia [ It can be expected that about 50% of an intravenous load of magnesium will be lost in the urine [6,23], and 50 mEq or more of magnesium may be needed within the first 12 h [5,6,23,24], It has been suggested that slower infusion rates decrease the urinary loss, since the plasma [Mg] determining the renal threshold will less likely be exceeded [25], Generally, to initiate therapy in a severely depleted patient, no more than 100 mEq of magnesium should be given during a 12-hour period, and consider able caution is needed with this dose [23]. For example, in a small number of magnesium-deficient subjects, Flink [12] noted that a rate of infusion of 50 mEq of magnesium every 12 h for 48 h resulted in an average serum [Mg] of about 3.0 mEq/1, and a rate of 100 mEq every 12 h was associated with an average serum level of about 4.0 mEq/1 (with no individual value exceeding 6.5 mEq/1).…”

Section: Parenteral Repletionmentioning

confidence: 99%

Management of Magnesium Depletion

Oster

Epstein²

1988

Am J Nephrol

View full text Add to dashboard Cite

In addition to the well-known complexities inherent in the recognition of hypomagnesemia and/or magnesium depletion, the management of magnesium deficiency oftentimes is not straightforward and requires the understanding of several important principles. Among these is that the avoidance of ineffective undertreatment of patients with symptomatic severe depletion may require parenteral administration of quite large amounts of magnesium for several days. This point is evident in the included case example describing a patient in whom the small amounts of magnesium given initially were entirely ineffective. The use of the various protocols to provide a patient with magnesium by the parenteral route requires consideration of several factors. The purpose of this paper is to provide the practitioner with a comprehensive, clinically useful review of the oral and parenteral therapy of patients with magnesium depletion.

show abstract

Primary hypomagnesaemia

Dudin

Teebi

1987

Eur J Pediatr

View full text Add to dashboard Cite

A case of primary hypomagnesaemia with secondary hypocalcaemia in an Arab girl of consanguineous parents is reported. She presented at the age of 3 weeks with generalised convulsions, was treated with magnesium supplements and followed up for 5 years during which she showed normal physical and psychomotor development. In view of the striking male preponderance among the reported cases and the presence of parental consanguinity in a few, the inheritance is discussed and genetic heterogeneity is suggested.

show abstract

Magnesium Malabsorption

Cited by 3 publications

References 60 publications

Changes in Some Serum and Heamatological Indices in Magnesium and Riboflavin Deficiency in Rats

Changes in Some Serum and Heamatological Indices in Magnesium and Riboflavin Deficiency in Rats

Management of Magnesium Depletion

Primary hypomagnesaemia

Contact Info

Product

Resources

About