Macular thickness measurements in healthy eyes using spectral optical coherence tomography

Abstract

AIM: The aim of the present study was to measure macular thickness in healthy eyes and find whether it changes with age. MATERIAL AND METHODS: We examined 163 healthy eyes of 84 healthy volunteers. In order to measure their macular thickness the patients were examined using spectral-domain optical coherent tomography (SD-ОСТ - iVue, Optovue). They were allocated into 6 age groups. RESULTS: The mean central macular thickness (inner circle - fovea centralis) was 248.9 ± 17.9 μm (mean ± SD), and the mean total macular thickness (an area including 9 subfields as defined by ETDRS) was 286.2 ± 13.9 μm (mean ± SD). We found that it correlated negatively with age (r = - 0.18; p = 0.03; Pearson correlation). CONCLUSION: We found a statistically significant decrease of mean macular thickness as age increased.

Macular thicknesses and their associations with ocular and demographic variables in black South Africans

“…18,22 The temporal and nasal quadrants were thinnest and thickest, respectively, for the outer macular (perifoveal) region (Table 2), which is consistent with the arrangement of fibres in the papillo-macular region. 23 We found that the BMI was positively correlated with macular thicknesses (Table 3). The association between obesity and diabetes mellitus (DM), particularly type 2 (non-insulin-dependent) DM, has been known for several hundred years.…”

<p>Central Macular Thickness in a Healthy Mexican Population Using Huvitz Optical Coherence Tomography</p>

“…7,9 Significant differences in the macular central subfield thickness (CST) have been reported in healthy subjects among different races, genders, and age groups; many differences were also found between several scan protocols and OCT units. 6,8,[10][11][12][13][14][15][16][17][18][19][20] Normative macular thickness values using different OCT units on a specific population are needed to identify reference values for many eye conditions. A normative database for macular thickness helps us determine if a patient falls within or outside normal values for his age and race; in a clinical research setting, this database would help us determine a patient's inclusion or exclusion criteria, additionally, if the treatment is meant to decrease macular thickness, we need to be sure that we have an abnormally thick retina at the beginning in order to adequately measure its variations.…”

Macular thickness measurements using Copernicus Spectral Domain Optical Coherence Tomography

“…Studies have reported normative data of macular thickness using various commercially available SDOCTs 4–12 . The macular thickness measurement for diagnostic function may differ with the population which is used as a database as well as the instrument which is being used.…”