Macular Evaluation wıth Spectral Domain Type Optic Coherence Tomography in Eyes with Acute Nonarteritic Ischemic Optic Neuropathy at the Presentation Visit

Dönmez, Oya; Kocaoğlu, Gamze; Yaman, Aylın; Bajin, Meltem Söylev; Saatçi, Ali Osman

doi:10.2174/1874364101711010017

Cited by 4 publications

(9 citation statements)

References 19 publications

(21 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Subsequent case reports by others have also described submacular fluid in NAION patients, who notably appeared to respond well to systemic corticosteroid treatment (2,3). A recent study by Donmez et al showed that 34.9% of 63 NAION patients had some evidence of subretinal fluid on macular OCT obtained during their initial evaluation, with 23.8% (15 patients) having subfoveal fluid (5). In the present study, we have continued to observe subretinal fluid in a majority of cases (64% of eyes, 70% of patients).…”

Section: Discussionmentioning

confidence: 99%

“…A recent article investigating OCT scans of the macula in the acute phase of NAION reported the novel finding of HRD in the outer retina in 15% of eyes (5). In the present study, we found that 44% of eyes had evidence of hyperreflective material, suggesting that HRD might be a phenomenon that has been overlooked to date.…”

Section: Discussionmentioning

confidence: 99%

“…The OCT scan that contained the highest number of hyperreflective dots was used for quantification. Hyperreflective dots were documented if $10 hyperreflective dots were noted (adapted from Donmez et al and Coscas et al) (5,10). Student t tests were run to compare BCVA between groups with and without hyperreflective dots.…”

Section: Subjects and Study Designmentioning

confidence: 99%

“…Case reports (2,3) and animal models (4) have corroborated these findings. Furthermore, other retinal findings, such as hyperreflective dots (HRD), have been documented in the outer retina in NAION (5). Recent publications have also suggested that vitreous abnormalities, namely, vitreopapillary traction (VPT), might play a role in NAION (6,7).…”

mentioning

confidence: 99%

See 3 more Smart Citations

Vitreoretinal Findings in Nonarteritic Ischemic Optic Neuropathy

Molaie¹,

Pramil²,

Hedges³

et al. 2021

Journal of Neuro-Ophthalmology

View full text Add to dashboard Cite

Background:Although nonarteritic anterior ischemic optic neuropathy (NAION) is considered a disorder that primarily affects the optic nerve head, optical coherence tomography (OCT) shows peripapillary and foveal subretinal fluid associated with optic disc swelling from NAION. We sought to further evaluate retinal and vitreous changes in patients with NAION.Methods:Patients diagnosed with NAION at the New England Eye Center between 2013 and 2017 were evaluated using OCT. The presence and distribution of subretinal fluid was analyzed. Evidence of other vitreoretinal changes, including vitreopapillary traction (VPT) and the presence of hyperreflective dots (HRD), were also determined.Results:Twenty-five eyes from 20 patients who presented within 4 weeks of symptom onset were assessed. Peripapillary subretinal fluid was seen in 16 eyes (64%). Of those eyes, the subretinal fluid extended into the macula in 4 eyes (16%). Visual acuity improved in 2 of 4 eyes after subfoveal fluid resolution. Intraretinal cysts located in the peripapillary region were seen in 8 eyes (32%), HRD were noted in 11 (44.0%). There was no evidence of VPT.Conclusions:A substantial number of patients with NAION have subretinal fluid on OCT, consistent with prior reports. Resolution of subfoveal fluid may result in some recovery of visual acuity. Other retinal changes, such as intraretinal cysts and HRD, are present but have unclear implications. We did not find evidence of a primary role of VPT in the pathophysiology of NAION.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Subjects and Study Designmentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Vitreoretinal Findings in Nonarteritic Ischemic Optic Neuropathy

Molaie¹,

Pramil²,

Hedges³

et al. 2021

Journal of Neuro-Ophthalmology

View full text Add to dashboard Cite

show abstract

“…On the other hand, multiple groups have analyzed macular fluid in eyes with acute AION with variable prevalence and distribution across the different retinal layers. 16 , 24–26 …”

Section: Introductionmentioning

confidence: 99%

Prevalence and Distribution of Macular Fluid with Central Retinal Artery Occlusion and Anterior Ischemic Optic Neuropathy

Fouad,

Hamza,

Wessam

2024

OPTH

View full text Add to dashboard Cite

Purpose To examine the prevalence and distribution of fluid within a cohort of eyes with acute central retinal artery occlusion (CRAO) and non-arteritic anterior ischemic optic neuropathy (AION) using optical coherence tomography (OCT). Methods A retrospective analysis of patient records and OCT imaging. Patients presenting with acute CRAO or AION who had available macular OCT imaging and no co-morbidities known to cause macular fluid were included in the analysis. Baseline characteristics, visual acuity (VA), and fluid presence and distribution among the retinal layers were recorded. Results In the 16 eyes with acute CRAO, fluid was noted in 5 eyes (31%), which was mainly subretinal (3 eyes) or intraretinal located within the outer retinal layers (3 eyes). Only one eye had inner retinal cysts. Of the 11 eyes with acute AION, fluid was present in 8 eyes (73%). Subretinal fluid was noted in 4 eyes and extended to the foveal area in 3 of them, and outer retinal versus inner retinal cysts were noted in 6 versus 3 eyes, respectively. None of the eyes showed hard exudate deposition. In the small subset of eyes with CRAO and macular fluid that were followed-up, VA improved, while in eyes with AION, VA remained stable. Conclusion Macular fluid on OCT is not an uncommon feature of acute CRAO and AION and is mainly distributed within the outer retinal layers or subretinal space. Fluid is an understudied feature of retinal and optic nerve head infarction and may have a role in predicting neuronal damage extent and visual outcome.

show abstract