Macroprolactinoma aos 6 anos de idade dificuldades diagnósticas: difficulties in diagnosis

Abstract

Prolactinoma is rare in childhood and adolescence. The earliest known diagnosis was reported in a patient at 8 years of age. We report the case of a sellar tumor found in a 6 years old girl. After a long symptomatic period she was brought for treatment. At this time she had partial papillar atrophy, hyperprolactinemia, and diminished reserve of growth hormone and cortisol. Due to rapid visual deterioration, she was submitted to a frontotemporal craniotomy for suspected craniopharyngioma. The tumor tissue immunohistochemistry was positive for prolactin. It is concluded that prolactinoma must be considered in differential diagnosis of sellar tumors in childhood since it benefits from a less aggressive therapy.

Microadenomas hipofisários: revisão de 95 casos

“…São classificados pelo tamanho: aqueles menores de 10 mm são microadenomas, e os maiores, macroadenomas. Sua apresentação clínica depende não só do tamanho da lesão, como da presença ou ausência de atividade hormonal, tipo de hormônio produzido e grau de extensão extra-selar, sendo raros nas crianças e em pacientes adultos com menos de 20 anos de idade (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14) .…”