Macroprolactinemia: prevalence and clinical characteristics in a cohort of hyperprolactinemic patients assessed for macroprolactinemia

Abstract

Among premenopausal women with macroPRL the most common complaints were: galactorrhea (23,5%), menstrual irregularities (29,4%), infertility (29,4%), while among those with true hyperPRL they were found in 45%, 50%, and 15% respectively. Some of the patients presented more than one symptom. No symptoms were reported in 22,2% of patients with macroPRL and 14,8% with true hyperPRL. Three male patients had macroPRL and symptoms: erectile dysfunction, infertility or galactorrhea. Two men with true hyperPRL presented erectile dysfunction with gynecomastia and headaches with visual disturbances (Table 2). Macroprolactinemia: prevalence and clinical characteristics in a cohort of hyperprolactinemic patients assessed for macroprolactinemia